posaconazole

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







26 Article(s)
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1 34937801 Accelerating Clinical Development of Idasanutlin through a Physiologically Based Pharmacokinetic Modeling Risk Assessment for CYP450 Isoenzyme-Related Drug-Drug Interactions. 2022 Mar 1
2 32472569 Tablets or oral suspension for posaconazole in lung transplant recipients? Consequences for trough concentrations of tacrolimus and everolimus. 2021 Feb 1
3 33398386 Dose adjustment of venetoclax when co-administered with posaconazole: clinical drug-drug interaction predictions using a PBPK approach. 2021 Apr 2
4 33677444 Choosing Antifungals for the Midostaurin-Treated Patient: Does CYP3A4 Outweigh Recommendations? A Brief Insight from Real Life. 2021 1
5 32514626 Antifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma. 2020 Jul 1
6 29255993 Prevalence and nature of statin drug-drug interactions in a university hospital by electronic health record mining. 2018 Apr 1
7 29368050 Effects of posaconazole (a strong CYP3A4 inhibitor), two new tablet formulations, and food on the pharmacokinetics of idasanutlin, an MDM2 antagonist, in patients with advanced solid tumors. 2018 Mar 1
8 29749631 Persistence of a Posaconazole-Mediated Drug-Drug Interaction With Ranolazine After Cessation of Posaconazole Administration: Impact of Obesity and Implications for Patient Safety. 2018 Nov 1
9 29851709 Sustained Impairment of Lurasidone Clearance After Discontinuation of Posaconazole: Impact of Obesity, and Implications for Patient Safety. 2018 Aug 1
10 29991575 Comparison of Antifungal Azole Interactions with Adult Cytochrome P450 3A4 versus Neonatal Cytochrome P450 3A7. 2018 Sep 1
11 26864621 Salvage Treatment of Mucormycosis Post-Liver Transplant With Posaconazole During Sirolimus Maintenance Immunosuppression. 2017 Apr 1
12 27545757 Clinical Drug-Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib. 2017 May 1
13 28161120 Management of Venetoclax-Posaconazole Interaction in Acute Myeloid Leukemia Patients: Evaluation of Dose Adjustments. 2017 Feb 3
14 27125217 Long QT Syndrome Leading to Multiple Cardiac Arrests After Posaconazole Administration in an Immune-Compromised Patient with Sepsis: An Unusual Case Report. 2016 Apr 29 1
15 27530708 Increased inhibition of cytochrome P450 3A4 with the tablet formulation of posaconazole. 2016 Oct 5
16 26232156 A clinical approach to solving discrepancies in therapeutic drug monitoring results for patients on sirolimus or tacrolimus: Towards personalized medicine, immunosuppression and pharmacogenomics. 2015 Oct 23 1
17 28975914 Posaconazole: An Update of Its Clinical Use. 2015 Oct 21 2
18 22176629 Effect of posaconazole on the pharmacokinetics of simvastatin and midazolam in healthy volunteers. 2012 Jan 1
19 22564264 Safety of posaconazole and sirolimus coadministration in allogeneic hematopoietic stem cell transplants. 2012 Sep 3
20 21126270 Posaconazole: clinical pharmacokinetics and drug interactions. 2011 Jan 1
21 20840439 Clinical pharmacodynamics and pharmacokinetics of the antifungal extended-spectrum triazole posaconazole: an overview. 2010 Oct 1
22 19196220 Effects of oral posaconazole on the pharmacokinetics of sirolimus. 2009 Mar 2
23 19302901 Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers. 2009 Feb 3
24 19346885 Posaconazole-increased vincristine neurotoxicity in a child: a case report. 2009 Apr 1
25 15066665 Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study. 2004 Apr 4
26 15311563 Posaconazole: a potent, extended-spectrum triazole anti-fungal for the treatment of serious fungal infections. 2004 Jun 1