Pioglitazone

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







14 Article(s)
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1 27599706 Physiologically Based Pharmacokinetic Modeling to Predict Drug-Drug Interactions with Efavirenz Involving Simultaneous Inducing and Inhibitory Effects on Cytochromes. 2017 Apr 1
2 26296069 Physiologically based pharmacokinetics model predicts the lack of inhibition by repaglinide on the metabolism of pioglitazone. 2015 Dec 1
3 22942318 Statistical methods for analysis of time-dependent inhibition of cytochrome p450 enzymes. 2012 Dec 1
4 18783297 General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information. 2008 1
5 17201456 Pharmacokinetic interactions with thiazolidinediones. 2007 1
6 16447051 Pioglitazone, an in vitro inhibitor of CYP2C8 and CYP3A4, does not increase the plasma concentrations of the CYP2C8 and CYP3A4 substrate repaglinide. 2006 Mar 3
7 16867170 Pioglitazone is metabolised by CYP2C8 and CYP3A4 in vitro: potential for interactions with CYP2C8 inhibitors. 2006 Jul 4
8 17214065 The pharmacokinetics of pioglitazone in Thai healthy subjects. 2006 Dec 1
9 15900286 Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics of pioglitazone. 2005 May 2
10 16283275 Effect of gemfibrozil on the pharmacokinetics of pioglitazone. 2005 Dec 1
11 16372821 Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance. 2005 1
12 12642470 Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition. 2003 Apr 2
13 11921435 Differentiating members of the thiazolidinedione class: a focus on safety. 2002 Mar-Apr 2
14 12463723 Pioglitazone: effect on CYP3A4 activity. 2002 Dec 3