Risperidone

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







40 Article(s)
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Pub. Year
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1 34903590 Intersystem Extrapolation Factors Are Substrate-Dependent for CYP3A4: Impact on Cytochrome P450 Reaction Phenotyping. 2022 Mar 2
2 34335273 Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone. 2021 1
3 31359271 Physiologically Based Pharmacokinetic Modelling to Describe the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone According to Cytochrome P450 2D6 Phenotypes. 2020 Jan 2
4 32276526 Cytochrome P450 (CYP450) Interactions Involving Atypical Antipsychotics are Common in Community-Dwelling Older Adults Treated for Behavioral and Psychological Symptoms of Dementia. 2020 Apr 8 1
5 32446424 High Doses of Drugs Extensively Metabolized by CYP3A4 Were Needed to Reach Therapeutic Concentrations in Two Patients Taking Inducers. 2020 Apr - Jun 1
6 32519344 CYP2D6 Genetic Polymorphisms and Risperidone Pharmacokinetics: A Systematic Review and Meta-analysis. 2020 Jul 1
7 29055041 The possible clinical impact of risperidone on P-glycoprotein-mediated transport of tacrolimus: A case report and in vitro study. 2018 Jan 1
8 29869546 The Use of Carbamazepine to Expedite Metabolism of Risperidone Long-Acting Injection Through Induction of CYP3A4 in a Patient With Extrapyramidal Symptoms. 2018 Jun 1 1
9 27993531 Effect of smoking on risperidone pharmacokinetics - A multifactorial approach to better predict the influence on drug metabolism. 2017 Jul 1
10 28160505 Cytochrome P450-mediated interaction between perazine and risperidone: implications for antipsychotic polypharmacy. 2017 Aug 1
11 27251417 Pharmacokinetic considerations in the treatment of hypertension in risperidone-medicated patients - thinking of clinically relevant CYP2D6 interactions. 2016 Aug 1
12 25868121 The Influence of the CYP3A4*22 Polymorphism and CYP2D6 Polymorphisms on Serum Concentrations of Aripiprazole, Haloperidol, Pimozide, and Risperidone in Psychiatric Patients. 2015 Jun 1
13 26387027 Evaluation of potential pharmacokinetic drug-drug interaction between armodafinil and risperidone in healthy adults. 2015 Nov 1
14 21518375 Effect of cytochrome P450 3A4 inhibitor ketoconazole on risperidone pharmacokinetics in healthy volunteers. 2012 Apr 4
15 28520384 Risperidone Therapy and CYP2D6 Genotype 2012 1
16 19395426 Relationship between response to risperidone, plasma concentrations of risperidone and CYP3A4 polymorphisms in schizophrenia patients. 2010 Jul 3
17 18094221 Effect of rifampin, an inducer of CYP3A and P-glycoprotein, on the pharmacokinetics of risperidone. 2008 Jan 2
18 18537577 Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions. 2008 Jun 1
19 18691984 Risk of discontinuation of risperidone after exposure to potentially interacting drugs: a nested case-control study in patients with schizophrenia. 2008 Jul 1
20 17214606 Metabolic drug interactions with newer antipsychotics: a comparative review. 2007 Jan 1
21 17381666 Rifampin, a cytochrome P450 3A inducer, decreases plasma concentrations of antipsychotic risperidone in healthy volunteers. 2007 Apr 2
22 15883149 The dosing of atypical antipsychotics. 2005 May-Jun 2
23 15910772 Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs. 2005 May 31 1
24 16226034 Effect of fluvoxamine on plasma risperidone concentrations in patients with schizophrenia. 2005 Dec 1
25 16321618 Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients. 2005 Nov 4
26 15270204 The role of cytochrome P450 enzymes in the metabolism of risperidone and its clinical relevance for drug interactions. 2004 Aug 1
27 12665390 Fatalities associated with therapeutic use and overdose of atypical antipsychotics. 2003 1
28 12670127 Interactions between the cytochrome P450 system and the second-generation antipsychotics. 2003 Mar 1
29 11978161 Extrapyramidal symptoms with ritonavir/indinavir plus risperidone. 2002 May 1
30 12172343 Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: a clinically relevant pharmacokinetic drug interaction. 2002 Aug 1
31 12186270 New antipsychotic agents for schizophrenia: pharmacokinetics and metabolism update. 2002 Jul 2
32 11476125 An evaluation of risperidone drug interactions. 2001 Aug 1
33 11560868 Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes. 2001 Oct 2
34 10771452 Identification of the major human liver cytochrome P450 isoform(s) responsible for the formation of the primary metabolites of ziprasidone and prediction of possible drug interactions. 2000 2
35 10843459 Biotransformation of post-clozapine antipsychotics: pharmacological implications. 2000 May 2
36 10942191 Plasma concentrations of risperidone and 9-hydroxyrisperidone: effect of comedication with carbamazepine or valproate. 2000 Aug 1
37 10048600 Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4. 1999 Feb 1
38 10422890 Drug metabolism and atypical antipsychotics. 1999 Jun 1
39 10453802 A pilot study on risperidone metabolism: the role of cytochromes P450 2D6 and 3A. 1999 Jul 3
40 9231305 Erythromycin interaction with risperidone or clomipramine in an adolescent. 1996 Summer 1