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33238041 | Inhibitory effects of astilbin, neoastilbin and isoastilbin on human cytochrome CYP3A4 and 2D6 activities. | 2021 Apr |
1 |
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34060409 | On the inhibition of cytochrome P450 3A4 by structurally diversified flavonoids. | 2021 Jun 1 |
2 |
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31756459 | Heterotropic activation of flavonoids on cytochrome P450 3A4: A case example of alleviating dronedarone-induced cytotoxicity. | 2020 Feb 1 |
4 |
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31639084 | Screening of flavonoid aglycons' metabolism mediated by the human liver cytochromes P450. | 2019 Dec 1 |
1 |
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29753067 | Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. | 2018 Sep 15 |
4 |
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30301254 | The Inhibitory Effect of Flavonoid Aglycones on the Metabolic Activity of CYP3A4 Enzyme. | 2018 Oct 7 |
4 |
| 7 |
30463833 | Assessment of Feng-Liao-Chang-Wei-Kang as a potential inducer of cytochrome P450 3A4 and pregnane X receptors. | 2018 Sep |
1 |
| 8 |
28462502 | Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative. | 2017 Aug |
1 |
| 9 |
28867739 | Inhibitory Effects of Juices Prepared from Individual Vegetables on CYP3A4 Activity in Recombinant CYP3A4 and LS180 Cells. | 2017 |
1 |
| 10 |
27107807 | In vitro effects of the citrus flavonoids diosmin, naringenin and naringin on the hepatic drug-metabolizing CYP3A enzyme in human, pig, mouse and fish. | 2016 Jun 15 |
2 |
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25684704 | Investigation of CYP3A4 and CYP2D6 Interactions of Withania somnifera and Centella asiatica in Human Liver Microsomes. | 2015 May |
2 |
| 12 |
24741320 | Three-dimensional quantitative structure-activity relationship and docking studies in a series of anthocyanin derivatives as cytochrome P450 3A4 inhibitors. | 2014 |
1 |
| 13 |
23188647 | Flavonoids and polymer derivatives as CYP3A4 inhibitors for improved oral drug bioavailability. | 2013 Feb |
4 |
| 14 |
20553580 | Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells. | 2010 Jun 16 |
4 |
| 15 |
19336903 | The structure-activity correlation on the inhibitory effects of flavonoids on cytochrome P450 3A activity. | 2009 Apr |
4 |
| 16 |
19766177 | CYP1A1 and CYP3A4 modulation by dietary flavonoids in human intestinal Caco-2 cells. | 2009 Dec 15 |
1 |
| 17 |
18191104 | Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes. | 2008 Mar 15 |
2 |
| 18 |
18420779 | Comparative analysis of CYP3A heteroactivation by steroid hormones and flavonoids in different in vitro systems and potential in vivo implications. | 2008 Jul |
1 |
| 19 |
17452418 | Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction. | 2007 Jul |
1 |
| 20 |
12695340 | Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products. | 2003 May |
1 |
| 21 |
11737987 | Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds. | 2001 Sep-Dec |
3 |
| 22 |
10801247 | Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. | 2000 Apr |
1 |
| 23 |
10871299 | Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression. | 2000 Jul |
1 |
| 24 |
9202751 | The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies. | 1997 May 12 |
1 |
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8844805 | Function and localization of cytochromes P450 involved in the metabolic activation of food-derived heterocyclic amines. | 1995 |
2 |