catechol

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







12 Article(s)
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1 34243013 Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play. 2021 Oct 1
2 34683865 Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics. 2021 Sep 28 1
3 20007670 Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator. 2010 Mar 1
4 20507089 Discovery tactics to mitigate toxicity risks due to reactive metabolite formation with 2-(2-hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3h)-one derivatives, potent calcium-sensing receptor antagonists and clinical candidate(s) for the treatment of osteoporosis. 2010 Jun 21 1
5 18407675 Assessment of the metabolism and intrinsic reactivity of a novel catechol metabolite. 2008 May 1
6 17570247 Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA. 2007 Jul 1
7 15319341 Kinetics and regulation of cytochrome P450-mediated etoposide metabolism. 2004 Sep 1
8 11459198 The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia. 2001 Jun 1
9 11473400 Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry. 2001 Jul 2
10 9714305 Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoforms. 1998 Jun 1 2
11 9789061 Association of CYP3A4 genotype with treatment-related leukemia. 1998 Oct 27 1
12 8114683 O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. 1994 Feb 2