12 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34243013 | Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play. | 2021 Oct | 1 |
2 | 34683865 | Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics. | 2021 Sep 28 | 1 |
3 | 20007670 | Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator. | 2010 Mar | 1 |
4 | 20507089 | Discovery tactics to mitigate toxicity risks due to reactive metabolite formation with 2-(2-hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3h)-one derivatives, potent calcium-sensing receptor antagonists and clinical candidate(s) for the treatment of osteoporosis. | 2010 Jun 21 | 1 |
5 | 18407675 | Assessment of the metabolism and intrinsic reactivity of a novel catechol metabolite. | 2008 May | 1 |
6 | 17570247 | Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA. | 2007 Jul | 1 |
7 | 15319341 | Kinetics and regulation of cytochrome P450-mediated etoposide metabolism. | 2004 Sep | 1 |
8 | 11459198 | The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia. | 2001 Jun | 1 |
9 | 11473400 | Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry. | 2001 Jul | 2 |
10 | 9714305 | Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoforms. | 1998 Jun 1 | 2 |
11 | 9789061 | Association of CYP3A4 genotype with treatment-related leukemia. | 1998 Oct 27 | 1 |
12 | 8114683 | O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. | 1994 Feb | 2 |