| 1 |
34447675 | Interaction of Hepatitis B Virus X Protein with the Pregnane X Receptor Enhances the Synergistic Effects of Aflatoxin B1 and Hepatitis B Virus on Promoting Hepatocarcinogenesis. | 2021 Aug 28 |
1 |
| 2 |
32423188 | Detoxification of Aflatoxin B1 Contaminated Maize Using Human CYP3A4. | 2020 Aug 28 |
1 |
| 3 |
31159144 | Non-coplanar and coplanar polychlorinated biphenyls potentiate genotoxicity of aflatoxin B1 in a human hepatocyte line by enhancing CYP1A2 and CYP3A4 expression. | 2019 Mar |
1 |
| 4 |
30142320 | The critical role of porcine cytochrome P450 3A46 in the bioactivation of aflatoxin B1. | 2018 Oct |
1 |
| 5 |
28436563 | An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae. | 2017 May |
3 |
| 6 |
28006013 | Procarcinogens - Determination and Evaluation by Yeast-Based Biosensor Transformed with Plasmids Incorporating RAD54 Reporter Construct and Cytochrome P450 Genes. | 2016 |
1 |
| 7 |
24168324 | Cytochrome P450 isoforms are differently up-regulated in aflatoxin B₁-exposed human lymphocytes and monocytes. | 2014 Feb |
1 |
| 8 |
25398138 | Cooperative binding of aflatoxin B1 by cytochrome P450 3A4: a computational study. | 2014 Dec 15 |
7 |
| 9 |
22524704 | Generation of proliferating human hepatocytes using Upcyte® technology: characterisation and applications in induction and cytotoxicity assays. | 2012 Oct |
1 |
| 10 |
21641981 | Aflatoxins upregulate CYP3A4 mRNA expression in a process that involves the PXR transcription factor. | 2011 Aug 28 |
1 |
| 11 |
20233841 | CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cells. | 2010 Jun |
1 |
| 12 |
20655369 | Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro. | 2010 Oct 5 |
1 |
| 13 |
18950609 | Metabolism Comparative Cytotoxicity Assay (MCCA) and Cytotoxic Metabolic Pathway Identification Assay (CMPIA) with cryopreserved human hepatocytes for the evaluation of metabolism-based cytotoxicity in vitro: proof-of-concept study with aflatoxin B1. | 2009 Apr 15 |
1 |
| 14 |
19298836 | A sensitive bioassay for the mycotoxin aflatoxin B(1), which also responds to the mycotoxins aflatoxin G(1) and T-2 toxin, using engineered baker's yeast. | 2009 Jun |
2 |
| 15 |
18347083 | Long-term functional stability of human HepaRG hepatocytes and use for chronic toxicity and genotoxicity studies. | 2008 Jun |
1 |
| 16 |
10771285 | Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism. | 2000 Apr 14 |
1 |
| 17 |
11465078 | Drug-metabolizing enzymes: mechanisms and functions. | 2000 Sep |
1 |
| 18 |
11189750 | Increased cytotoxicity of food-borne mycotoxins toward human cell lines in vitro via enhanced cytochrome p450 expression using the MTT bioassay. | 1999 Nov |
1 |
| 19 |
8608525 | Urinary 6 beta-hydroxycortisol excretion in Hong Kong Chinese patients with hepatocellular carcinoma and other chronic liver diseases. | 1996 Apr 15 |
1 |
| 20 |
8625305 | Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention. | 1996 May 15 |
1 |
| 21 |
8806738 | Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells. | 1996 Aug 15 |
1 |
| 22 |
8975785 | The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4. | 1996 Dec |
1 |
| 23 |
7545582 | A NIH/3T3 cell line stably expressing human cytochrome P450-3A4 used in combination with a lacZ' shuttle vector to study mutagenicity. | 1995 May 26 |
2 |
| 24 |
7575636 | Tiamulin inhibits human CYP3A4 activity in an NIH/3T3 cell line stably expressing CYP3A4 cDNA. | 1995 Sep 7 |
2 |
| 25 |
7585637 | Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture. | 1995 Dec 1 |
1 |
| 26 |
7850790 | Fetus-specific CYP3A7 and adult-specific CYP3A4 expressed in Chinese hamster CHL cells have similar capacity to activate carcinogenic mycotoxins. | 1995 Feb 15 |
1 |
| 27 |
8204093 | Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms. | 1994 May 18 |
2 |
| 28 |
8261428 | Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1. | 1994 Jan 1 |
1 |
| 29 |
1302569 | Urinary 6 beta-hydroxycortisol/cortisol ratios measured by high-performance liquid chromatography for use as a biomarker for the human cytochrome P-450 3A4. | 1992 Nov-Dec |
1 |
| 30 |
1643634 | Role of cytochrome P-450 from the human CYP3A gene family in the potentiation of morpholino doxorubicin by human liver microsomes. | 1992 Aug 15 |
1 |
| 31 |
1899812 | The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and CYP2A3. | 1991 Feb |
1 |