31 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 32386926 | Unusually high serum levels of clozapine associated with genetic polymorphism of CYP3A enzymes. | 2021 Mar | 1 |
2 | 32888176 | Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4. | 2021 Feb | 6 |
3 | 32103962 | The CYP2C19*2 and CYP2C19*17 Polymorphisms Influence Responses to Clozapine for the Treatment of Schizophrenia. | 2020 | 2 |
4 | 33277605 | Association of clozapine-related metabolic disturbances with CYP3A4 expression in patients with schizophrenia. | 2020 Dec 4 | 8 |
5 | 29155491 | Variation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors. | 2018 Apr | 3 |
6 | 28340122 | Potential Role of Patients' CYP3A-Status in Clozapine Pharmacokinetics. | 2017 Jul 1 | 9 |
7 | 27164071 | In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism. | 2016 May 6 | 1 |
8 | 23297297 | Characterization of human cytochrome P450s involved in the bioactivation of clozapine. | 2013 Mar | 2 |
9 | 22113252 | Interaction of St John's wort (Hypericum perforatum) with clozapine. | 2012 Mar | 1 |
10 | 28520368 | Clozapine Therapy and CYP Genotype | 2012 | 2 |
11 | 19593168 | ABCB1 and cytochrome P450 polymorphisms: clinical pharmacogenetics of clozapine. | 2009 Aug | 1 |
12 | 19801957 | The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test. | 2009 Nov | 1 |
13 | 19843060 | In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation. | 2009 Oct | 1 |
14 | 18537577 | Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions. | 2008 Jun | 1 |
15 | 18809730 | Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes. | 2008 Dec | 2 |
16 | 17392390 | Risk assessment for drug-drug interaction caused by metabolism-based inhibition of CYP3A using automated in vitro assay systems and its application in the early drug discovery process. | 2007 Jul | 1 |
17 | 17504220 | CYP-mediated clozapine interactions: how predictable are they? | 2007 May | 1 |
18 | 16184070 | Examining concentration-dependent toxicity of clozapine: role of therapeutic drug monitoring. | 2005 Sep | 2 |
19 | 12665390 | Fatalities associated with therapeutic use and overdose of atypical antipsychotics. | 2003 | 1 |
20 | 12670127 | Interactions between the cytochrome P450 system and the second-generation antipsychotics. | 2003 Mar | 1 |
21 | 11504269 | Contributions of five human cytochrome P450 isoforms to the N-demethylation of clozapine in vitro at low and high concentrations. | 2001 Aug | 1 |
22 | 10359460 | Characterization of the human hepatic cytochromes P450 involved in the in vitro oxidation of clozapine. | 1999 Apr 1 | 1 |
23 | 10365650 | Small effects of valproic acid on the plasma concentrations of clozapine and its major metabolites in patients with schizophrenic or affective disorders. | 1999 Jun | 1 |
24 | 10379638 | Absence of interaction between erythromycin and a single dose of clozapine. | 1999 May | 2 |
25 | 10422890 | Drug metabolism and atypical antipsychotics. | 1999 Jun | 2 |
26 | 10435773 | The effect of nefazodone on clozapine plasma concentrations. | 1999 May | 2 |
27 | 9626923 | Serum concentrations of clozapine and N-desmethylclozapine are unaffected by the potent CYP3A4 inhibitor itraconazole. | 1998 Apr | 3 |
28 | 9840430 | Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine. | 1998 Nov | 3 |
29 | 9384460 | The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine. | 1997 Nov | 4 |
30 | 8866916 | In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A. | 1996 Mar | 1 |
31 | 7974626 | Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: evidence from a therapeutic drug monitoring service. | 1994 Aug | 1 |