Oxygen

von Hippel-Lindau tumor suppressor ; Mus musculus







27 Article(s)
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1 31583505 Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia. 2020 May 1
2 31142573 Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation. 2019 Jul 1
3 26856676 Increased myeloid cell hypoxia-inducible factor-1 delays obliterative airway disease in the mouse. 2016 May 1
4 24508125 Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver. 2014 Apr 1
5 25385837 Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia. 2014 Dec 1
6 24298056 VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus. 2013 Dec 1 1
7 22299048 Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts. 2012 1
8 21217781 Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death. 2011 May 5 3
9 21811636 Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression. 2011 1
10 20140661 Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha. 2010 May 2
11 20522651 Deletion of von Hippel-Lindau in glomerular podocytes results in glomerular basement membrane thickening, ectopic subepithelial deposition of collagen {alpha}1{alpha}2{alpha}1(IV), expression of neuroglobin, and proteinuria. 2010 Jul 1
12 19033400 A role for von Hippel-Lindau protein in pancreatic beta-cell function. 2009 Feb 3
13 19065050 Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. 2009 Jan 1
14 19671042 The VHL tumor suppressor: master regulator of HIF. 2009 1
15 18219317 The VHL tumor suppressor and HIF: insights from genetic studies in mice. 2008 Apr 2
16 18423190 O2 sensing: only skin deep? 2008 Apr 18 1
17 18490920 Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice. 2008 Sep 11 1
18 17203215 von Hippel Lindau tumor suppressor regulates hepatic glucose metabolism by controlling expression of glucose transporter 2 and glucose 6-phosphatase. 2007 Feb 2
19 17609290 Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease. 2007 Oct 1
20 17998050 Transgenic models to understand hypoxia-inducible factor function. 2007 1
21 16537898 pVHL function is essential for endothelial extracellular matrix deposition. 2006 Apr 1
22 15908240 The VHL tumor suppressor in development and disease: functional studies in mice by conditional gene targeting. 2005 Aug-Oct 1
23 16024619 Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor. 2005 Jul 15 1
24 14985465 Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors. 2004 Feb 2
25 15448019 The von Hippel-Lindau tumor suppressor gene and kidney cancer. 2004 Sep 15 2
26 12559177 Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth. 2003 Jan 1
27 11336512 Human cytotrophoblast expression of the von Hippel-Lindau protein is downregulated during uterine invasion in situ and upregulated by hypoxia in vitro. 2001 May 15 1