Guanosine Triphosphate

Rac family small GTPase 2 ; Homo sapiens







41 Article(s)
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1 35596857 Combined Immunodeficiency Caused by a Novel De Novo Gain-of-Function RAC2 Mutation. 2022 May 21 2
2 32636302 The molecular basis for immune dysregulation by the hyperactivated E62K mutant of the GTPase RAC2. 2020 Aug 21 1
3 32765284 Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis. 2020 2
4 30723080 Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects. 2019 May 2 5
5 31071452 Heterozygous activating mutation in RAC2 causes infantile-onset combined immunodeficiency with susceptibility to viral infections. 2019 Aug 2
6 29757466 NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits. 2018 Nov 1
7 30271600 RASAL3 preferentially stimulates GTP hydrolysis of the Rho family small GTPase Rac2. 2018 Sep 1
8 23603360 Interaction characteristics of Plexin-B1 with Rho family proteins. 2013 May 17 1
9 22902632 S-glutathionylation regulates GTP-binding of Rac2. 2012 Sep 7 3
10 21378159 Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2. 2011 May 6 1
11 21680873 An evolutionary analysis of RAC2 identifies haplotypes associated with human autoimmune diseases. 2011 Dec 1
12 22106281 Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2. 2011 Dec 6 2
13 17312384 Overexpression of RhoE in Non-small Cell Lung Cancer (NSCLC) is associated with smoking and correlates with DNA copy number changes. 2007 Mar 1
14 17975262 Rac2 GTPase activation by angiotensin II is modulated by Ca2+/calcineurin and mitogen-activated protein kinases in human neutrophils. 2007 Nov 1
15 16085653 Mechanisms of statin-mediated inhibition of small G-protein function. 2005 Oct 7 1
16 15169870 Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis. 2004 Aug 1
17 12183443 Bombesin stimulates invasion and migration of Isreco1 colon carcinoma cells in a Rho-dependent manner. 2002 Aug 15 1
18 11278678 Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency. 2001 May 11 2
19 11403569 Blot overlays with 32P-labeled fusion proteins. 2001 Jul 1
20 10758162 Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation. 2000 Apr 25 1
21 10894930 The small GTPase RAC3 gene is located within chromosome band 17q25.3 outside and telomeric of a region commonly deleted in breast and ovarian tumours. 2000 1
22 9012677 Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator. 1997 Jan 21 1
23 9228059 Rac binding to p67(phox). Structural basis for interactions of the Rac1 effector region and insert region with components of the respiratory burst oxidase. 1997 Jul 25 1
24 9252344 Characterization of RAC3, a novel member of the Rho family. 1997 Aug 15 1
25 7479768 Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family. 1995 Oct 24 2
26 7852400 Low molecular weight GTP-binding proteins in HL-60 granulocytes. Assessment of the role of ARF and of a 50-kDa cytosolic protein in phospholipase D activation. 1995 Feb 17 1
27 7980444 SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism. 1994 Nov 1 1
28 8071333 p67-phox enhances the binding of p47-phox to the human neutrophil respiratory burst oxidase complex. 1994 Sep 2 1
29 8089125 Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac. 1994 Sep 23 1
30 8117279 The small GTP-binding protein rac is not recruited to the plasma membrane upon NADPH oxidase activation in human neutrophils. 1994 Feb 15 1
31 8141770 Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane. 1994 Mar 15 1
32 8282094 Regulation of phagocyte function by low molecular weight GTP-binding proteins. 1993 Nov 2
33 8305740 Regulation of NADPH oxidase activity by Rac GTPase activating protein(s). 1993 Nov 2
34 8387355 Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase. 1993 Mar 2
35 1328203 Inhibition of superoxide production in B lymphocytes by rac antisense oligonucleotides. 1992 Oct 15 1
36 1331090 Purification and characterization of Rac 2. A cytosolic GTP-binding protein that regulates human neutrophil NADPH oxidase. 1992 Nov 25 1
37 1464587 Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase. 1992 Dec 25 3
38 1660188 Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2. 1991 Dec 6 1
39 1903399 Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA. 1991 May 25 2
40 2111992 A small GTP-binding protein (G protein) recognized by smg p25A GDP dissociation inhibitor (GDI) in human platelet membranes and GDI for this small G protein in human platelet cytosol. 1990 May 16 1
41 2119580 Isoprenylation of the low molecular mass GTP-binding proteins rac 1 and rac 2: possible role in membrane localization. 1990 Sep 14 2