| 1 |
31053884 | The effect and molecular mechanism of statins on the expression of human anti-coagulation genes. | 2019 Oct |
1 |
| 2 |
31754207 | The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation. | 2019 Nov 21 |
1 |
| 3 |
28344327 | Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells. | 2017 Mar 27 |
1 |
| 4 |
28554582 | Geranylgeraniol prevents the simvastatin-induced PCSK9 expression: Role of the small G protein Rac1. | 2017 Aug |
4 |
| 5 |
29039527 | Simvastatin inhibits the expression of stemness‑related genes and the metastatic invasion of human cancer cells via destruction of the cytoskeleton. | 2017 Dec |
1 |
| 6 |
29236027 | Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer. | 2017 Dec 13 |
2 |
| 7 |
26761203 | Simvastatin Ameliorates Matrix Stiffness-Mediated Endothelial Monolayer Disruption. | 2016 |
1 |
| 8 |
27470565 | Simvastatin inhibits glucose uptake activity and GLUT4 translocation through suppression of the IR/IRS-1/Akt signaling in C2C12 myotubes. | 2016 Oct |
1 |
| 9 |
26658759 | Simvastatin suppresses breast cancer cell proliferation induced by senescent cells. | 2015 Dec 14 |
1 |
| 10 |
23559002 | Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases. | 2013 Apr 4 |
5 |
| 11 |
23794945 | Angiotensin receptor blockers and statins could alleviate atrial fibrosis via regulating platelet-derived growth factor/Rac1/nuclear factor-kappa B Axis. | 2013 |
3 |
| 12 |
23817226 | Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. | 2013 |
4 |
| 13 |
20946258 | Simvastatin inhibits glucose-stimulated vascular smooth muscle cell migration involving increased expression of RhoB and a block of Ras/Akt signal. | 2012 Apr |
1 |
| 14 |
21334995 | Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity. | 2011 May |
5 |
| 15 |
18992741 | Role for protein geranylgeranylation in adult T-cell leukemia cell survival. | 2009 Jan 15 |
1 |
| 16 |
19825520 | Pharmacological inhibitors of the mevalonate pathway activate pro-IL-1 processing and IL-1 release by human monocytes. | 2009 Sep |
1 |
| 17 |
18172037 | Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling. | 2008 Jan 22 |
2 |
| 18 |
18658277 | Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition. | 2008 Oct |
1 |
| 19 |
18684863 | HMG-CoA reductase inhibition induces IL-1beta release through Rac1/PI3K/PKB-dependent caspase-1 activation. | 2008 Nov 1 |
3 |
| 20 |
17303772 | Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation. | 2007 May |
3 |
| 21 |
17513949 | Angiotensin II type 1 receptor expression in polymorphonuclear leukocytes from high-risk subjects: changes after treatment with simvastatin. | 2007 May |
1 |
| 22 |
16723648 | Simvastatin decreases IL-6 and IL-8 production in epithelial cells. | 2006 Jun |
1 |
| 23 |
12417261 | Differential effect of simvastatin on activation of Rac(1) vs. activation of the heat shock protein 27-mediated pathway upon oxidative stress, in human smooth muscle cells. | 2002 Nov 15 |
2 |