2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

Rac family small GTPase 1 ; Homo sapiens







17 Article(s)
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1 30620754 Ligand-activated PPARδ inhibits angiotensin II-stimulated hypertrophy of vascular smooth muscle cells by targeting ROS. 2019 1
2 30021868 Distinct Roles of Small GTPases Rac1 and Rac2 in Histamine H4 Receptor-Mediated Chemotaxis of Mast Cells. 2018 Oct 1
3 28386321 Acid fibroblast growth factor preserves blood-brain barrier integrity by activating the PI3K-Akt-Rac1 pathway and inhibiting RhoA following traumatic brain injury. 2017 1
4 26687235 bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury. 2016 Dec 1
5 26207671 Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression. 2015 1
6 21318349 mTOR mediates RhoA-dependent leptin-induced cardiomyocyte hypertrophy. 2011 Jun 1
7 21980400 PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells. 2011 1
8 20980837 Laminin regulates PI3K basal localization and activation to sustain STAT5 activation. 2010 Nov 1 1
9 19726546 Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism. 2009 Nov 1
10 17300916 Regulator of G-protein signalling 3 redirects prototypical Gi-coupled receptors from Rac1 to RhoA activation. 2007 Jun 1
11 16395716 Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation. 2006 Jun 15 1
12 16195373 Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin. 2005 Oct 1
13 12816861 Tie-2-dependent activation of RhoA and Rac1 participates in endothelial cell motility triggered by angiopoietin-1. 2003 Oct 1 1
14 11726672 Flt-1-mediated down-regulation of endothelial cell proliferation through pertussis toxin-sensitive G proteins, beta gamma subunits, small GTPase CDC42, and partly by Rac-1. 2002 Feb 8 1
15 12384416 Activation of Rac-1, Rac-2, and Cdc42 by hemopoietic growth factors or cross-linking of the B-lymphocyte receptor for antigen. 2002 Nov 1 1
16 10617634 Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1. 2000 Jan 7 1
17 11062502 Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells. 2000 Nov 1