Ceramides

ceramide synthase 2 ; Homo sapiens







28 Article(s)
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1 34400330 Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death. 2022 Apr 6 1
2 35626132 diTFPP, a Phenoxyphenol, Sensitizes Hepatocellular Carcinoma Cells to C2-Ceramide-Induced Autophagic Stress by Increasing Oxidative Stress and ER Stress Accompanied by LAMP2 Hypoglycosylation. 2022 May 20 1
3 32374916 C24-Ceramide Drives Gallbladder Cancer Progression Through Directly Targeting Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Gamma to Facilitate Mammalian Target of Rapamycin Signaling Activation. 2021 Feb 2
4 33414460 Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. 2021 Jan 4 2
5 33515546 Ceramide synthase 2 deletion decreases the infectivity of HIV-1. 2021 Jan-Jun 2
6 33568634 Alternative splicing of ceramide synthase 2 alters levels of specific ceramides and modulates cancer cell proliferation and migration in Luminal B breast cancer subtype. 2021 Feb 10 1
7 33852174 Phosphorylated LASS2 inhibits prostate carcinogenesis via negative regulation of Wnt/β-catenin signaling. 2021 Apr 14 1
8 34647453 Mapping Sphingolipid Metabolism Pathways during Phagosomal Maturation. 2021 Dec 17 1
9 31544710 Targeting Ceramide Metabolism in Hepatocellular Carcinoma: New Points for Therapeutic Intervention. 2020 1
10 31785811 The metabolic pathway of sphingolipids biosynthesis and signaling in Entamoeba histolytica. 2020 Feb 12 1
11 32356173 Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer's Disease. 2020 Jun 1
12 29632068 Eleven residues determine the acyl chain specificity of ceramide synthases. 2018 Jun 22 1
13 30059758 Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy. 2018 Oct 2
14 30251650 Widespread tissue distribution and synthetic pathway of polyunsaturated C24:2 sphingolipids in mammals. 2018 Dec 1
15 27255818 Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease. 2016 Jul 2
16 27775668 Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide. 2016 Oct 21 2
17 25403920 A three-step assay for ceramide synthase activity using a fluorescent substrate and HPLC. 2015 Jan 1
18 26113602 Development of pheochromocytoma in ceramide synthase 2 null mice. 2015 Aug 1
19 25295789 CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. 2014 Oct 7 3
20 25356388 Reduced ceramide synthase 2 activity causes progressive myoclonic epilepsy. 2014 Feb 1
21 23538298 The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS. 2013 Jul 4
22 22230369 Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth. 2012 Apr 1
23 22579584 A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells. 2012 Jul 2
24 20591223 TMSG-1 and its roles in tumor biology. 2010 Jul 1
25 19279183 Ceramide synthases and ceramide levels are increased in breast cancer tissue. 2009 May 1
26 19728861 Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response. 2009 Nov 11 7
27 18165233 Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. 2008 Feb 29 1
28 15823095 Mammalian Lass6 and its related family members regulate synthesis of specific ceramides. 2005 Aug 15 2