Phorbol Esters

glycosylphosphatidylinositol specific phospholipase D1 ; Homo sapiens







56 Article(s)
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1 31311871 A real-time, click chemistry imaging approach reveals stimulus-specific subcellular locations of phospholipase D activity. 2019 Jul 30 1
2 24830864 Enhanced diacylglycerol production by phospholipase D activation is responsible for abnormal increase in concanavalin A cap formation in polymorphonuclear leukocytes from Chediak-Higashi syndrome (beige) mice. 2014 Jul 1
3 25137020 Phorbol ester stimulates ethanolamine release from the metastatic basal prostate cancer cell line PC3 but not from prostate epithelial cell lines LNCaP and P4E6. 2014 Oct 14 1
4 18523140 Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells. 2008 Sep 1
5 15389577 Studies of the roles of ADP-ribosylation factors and phospholipase D in phorbol ester-induced membrane ruffling. 2005 Feb 1
6 15843515 An essential role for phospholipase D in the activation of protein kinase C and degranulation in mast cells. 2005 May 1 1
7 16341931 Expression of MARCKS effector domain mutants alters phospholipase D activity and cytoskeletal morphology of SK-N-MC neuroblastoma cells. 2005 Nov 2
8 15081395 Expression and regulation of phospholipase D isoforms in sphingosine and phorbol ester-stimulated glioma C6 cells. 2004 May 7 2
9 15556619 Phorbol ester-induced differentiation of L6 myogenic cells involves phospholipase D activation. 2004 Nov 19 1
10 14646617 Expression and regulation of phospholipase D isoenzymes in human melanoma cells and primary melanocytes. 2003 Dec 3
11 11314048 Modulation of phospholipase D by hexadecylphosphorylcholine: a putative novel mechanism for its antitumoral activity. 2001 Mar 1 1
12 11336804 Hormonal regulation of phospholipase D activity in Ca(2+) transporting cells of rabbit connecting tubule and cortical collecting duct. 2001 Apr 23 1
13 11380624 Requirement of Syk-phospholipase C-gamma2 pathway for phorbol ester-induced phospholipase D activation in DT40 cells. 2001 May 5
14 11687572 Regulation of constitutive protein transit by phospholipase D in HT29-cl19A cells. 2001 Dec 28 1
15 10709112 Changes in phospholipase D isoform activity and expression in multidrug-resistant human cancer cells. 2000 Mar 15 1
16 10830309 The activation of phospholipase D by endothelin-1, angiotensin II, and platelet-derived growth factor in vascular smooth muscle A10 cells is mediated by small G proteins of the ADP-ribosylation factor family. 2000 Jun 1
17 11018470 Activation of phospholipase D by PKC and GTPgammaS in human neuroblastoma cells overexpressing MARCKS. 2000 Sep 27 1
18 9873009 Phospholipase D mediates matrix metalloproteinase-9 secretion in phorbol ester-stimulated human fibrosarcoma cells. 1999 Jan 8 1
19 10049506 Overexpression of protein kinase C-epsilon and its regulatory domains in fibroblasts inhibits phorbol ester-induced phospholipase D activity. 1999 Mar 1 1
20 10049738 Ral and Rho-dependent activation of phospholipase D in v-Raf-transformed cells. 1999 Feb 16 1
21 10597278 The human papillomavirus type 16 E5 protein modulates phospholipase C-gamma-1 activity and phosphatidyl inositol turnover in mouse fibroblasts. 1999 Nov 18 1
22 9516439 Specific inhibition of phorbol ester-stimulated phospholipase D by Clostridium sordellii lethal toxin and Clostridium difficile toxin B-1470 in HEK-293 cells. Restoration by Ral GTPases. 1998 Mar 27 2
23 9572295 Functional coupling of the NK1 tachykinin receptor to phospholipase D in chinese hamster ovary cells and astrocytoma cells. 1998 May 1
24 9593849 Phorbol ester stimulation of phosphatidylcholine synthesis requires expression of both protein kinase C-alpha and phospholipase D. 1998 May 20 1
25 9639664 Phospholipase D activity is altered in X-linked adrenoleukodystrophy heterozygous carriers, but not in hemizygous patients. 1998 Jul 1 2
26 9001386 Inhibition of phorbol ester-stimulated phospholipase D activity by chronic tamoxifen treatment in breast cancer cells. 1997 Jan 3 2
27 9052757 Tamoxifen activates cellular phospholipase C and D and elicits protein kinase C translocation. 1997 Mar 4 2
28 9143362 Inhibition of GTP gamma S-dependent phospholipase D and Rho membrane association by calphostin is independent of protein kinase C catalytic activity. 1997 May 1 3
29 9256242 Alkyl lysophospholipids inhibit phorbol ester-stimulated phospholipase D activity and DNA synthesis in fibroblasts. 1997 Jul 28 1
30 9346296 Characteristics of protein-kinase-C- and ADP-ribosylation-factor-stimulated phospholipase D activities in human embryonic kidney cells. 1997 Sep 1 2
31 9395070 Ro31-8220 inhibits protein kinase C to block the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells: p70 S6 kinase and MAPKAP kinase-1beta do not function downstream of PKC in activating PLD. 1997 Nov 3 4
32 8579603 Involvement of vicinal dithiols in differential regulation of fMLP and phorbol ester-activated phospholipase D in stimulated human neutrophils. 1996 Jan 26 2
33 8626805 Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activity. 1996 Feb 23 1
34 8753793 Enhanced phospholipase D activity and altered morphology in RhoA-overexpressing RAT1 fibroblasts. 1996 Aug 14 1
35 8855796 Regulation and metabolic role of phospholipase D activity in human thyroid and cultured dog thyrocytes. 1996 Oct 1
36 8898346 Differential involvement of calcium channels and protein kinase-C activity in GnRH-induced phospholipase-C, -A2 and -D activation in a gonadotrope cell line (alpha T3-1). 1996 Aug 30 1
37 8910539 Protein kinase Calpha is a major mediator of the stimulatory effect of phorbol ester on phospholipase D-mediated hydrolysis of phosphatidylethanolamine. 1996 Nov 15 1
38 8955215 Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line. 1996 Dec 15 1
39 7559408 ADP-ribosylation factor translocation correlates with potentiation of GTP gamma S-stimulated phospholipase D activity in membrane fractions of HL-60 cells. 1995 Sep 29 2
40 7755632 Potential role of protein phosphorylation in GTP-gamma-S-dependent activation of phospholipase D. 1995 May 16 2
41 7890622 Phosphatidylinositol 4,5-bisphosphate synthesis is required for activation of phospholipase D in U937 cells. 1995 Mar 10 2
42 7916902 Novel ketoepoxides block phospholipase D activation and tumor cell invasion. 1994 Aug 1
43 7945188 Phorbol ester selectively stimulates the phospholipase D-mediated hydrolysis of phosphatidylethanolamine in multidrug-resistant MCF-7 human breast carcinoma cells. 1994 Sep 15 1
44 8053546 A fluorescent assay for agonist-activated phospholipase D in mammalian cell extracts. 1994 Apr 2
45 8110192 Expression and secretion of glycosylphosphatidylinositol-specific phospholipase D by myeloid cell lines. 1994 Feb 1 1
46 8129736 The zinc chelator 1,10-phenanthroline enhances the stimulatory effects of protein kinase C activators and staurosporine, but not sphingosine and H2O2, on phospholipase D activity in NIH 3T3 fibroblasts. 1994 Feb 15 1
47 11550712 Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes. 1994 Dec 1
48 8338512 GTP gamma S and phorbol ester act synergistically to stimulate both Ca(2+)-independent secretion and phospholipase D activity in permeabilized human platelets. Inhibition by BAPTA and analogues. 1993 Jan 25 1
49 8392931 Rapid attenuation of receptor-induced diacylglycerol and phosphatidic acid by phospholipase D-mediated transphosphatidylation: formation of bisphosphatidic acid. 1993 Jul 1
50 8504157 Phospholipase D activity of human amnion cells stimulated with phorbol ester and bradykinin. 1993 Jun 12 1