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33858507 | Arsenic trioxide synergistically promotes the antileukaemic activity of venetoclax by downregulating Mcl-1 in acute myeloid leukaemia cells. | 2021 Apr 15 |
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34560123 | Enhanced GRP78 protein expression via the IRE1α/ASK1/p38 MAPK pathway during As2O3-induced endoplasmic reticulum stress in BEAS-2B cells. | 2021 Oct |
1 |
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32683294 | Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways. | 2020 Oct 10 |
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25758096 | The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation. | 2015 Jul |
2 |
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25983101 | ANXA1 silencing increases the sensitivity of cancer cells to low-concentration arsenic trioxide treatment by inhibiting ERK MAPK activation. | 2015 Jul-Aug |
6 |
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24307199 | Regulation of death induction and chemosensitizing action of 3-bromopyruvate in myeloid leukemia cells: energy depletion, oxidative stress, and protein kinase activity modulation. | 2014 Feb |
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24788596 | Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. | 2014 Jun |
1 |
| 8 |
25506699 | Apoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic trioxide and glycolytic inhibitors, and regulation by oxidative stress and protein kinase activities. | 2014 |
2 |
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22751450 | Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells. | 2013 Feb |
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23178716 | SnoN/SkiL expression is modulated via arsenic trioxide-induced activation of the PI3K/AKT pathway in ovarian cancer cells. | 2013 Jan 4 |
1 |
| 11 |
24004656 | Importance of ERK activation in As2O3-induced differentiation and promyelocytic leukemia nuclear bodies formation in neuroblastoma cells. | 2013 Nov |
4 |
| 12 |
24392034 | Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer. | 2013 |
2 |
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21523454 | Assessment of the involvement of oxidative stress and Mitogen-Activated Protein Kinase signaling pathways in the cytotoxic effects of arsenic trioxide and its combination with sulindac or its metabolites: sulindac sulfide and sulindac sulfone on human leukemic cell lines. | 2012 Jun |
2 |
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22532027 | NADPH oxidase-produced superoxide mediates EGFR transactivation by c-Src in arsenic trioxide-stimulated human keratinocytes. | 2012 Jun |
3 |
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20799280 | Arsenic trioxide induces apoptosis through JNK and ERK in human mesothelioma cells. | 2011 Mar |
3 |
| 16 |
21278055 | Involvement of glycogen synthase kinase-3β in arsenic trioxide-induced p21 expression. | 2011 May |
2 |
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20129490 | Arsenic trioxide-mediated antiplatelet activity: pivotal role of the phospholipase C gamma 2-protein kinase C-p38 MAPK cascade. | 2010 Feb |
5 |
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20615082 | Arsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells. | 2010 Sep |
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| 19 |
19038232 | Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation. | 2009 Feb 1 |
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19060284 | Antitumor activity of arsenic trioxide on retinoblastoma: cell differentiation and apoptosis depending on arsenic trioxide concentration. | 2009 Apr |
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| 21 |
19428345 | Enhancement of esculetin on arsenic trioxide-provoked apoptosis in human leukemia U937 cells. | 2009 Jun 15 |
2 |
| 22 |
18728151 | Novel human neutrophil agonistic properties of arsenic trioxide: involvement of p38 mitogen-activated protein kinase and/or c-jun NH2-terminal MAPK but not extracellular signal-regulated kinases-1/2. | 2008 Dec |
4 |
| 23 |
15961274 | As2O3-induced c-Src/EGFR/ERK signaling is via Sp1 binding sites to stimulate p21WAF1/CIP1 expression in human epidermoid carcinoma A431 cells. | 2006 Feb |
3 |
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16972261 | Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis. | 2006 Dec |
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| 25 |
17168655 | Arsenic trioxide in hematological malignancies: the new discovery of an ancient drug. | 2006 Dec |
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| 26 |
15538402 | Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells. | 2005 Feb |
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| 27 |
16445569 | Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells. | 2005 Dec |
2 |
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14610070 | 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione. | 2004 Jan 30 |
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12754411 | Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells. | 2003 Apr 30 |
2 |
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12296996 | Arsenic trioxide induces apoptosis in chronic myelogenous leukemia K562 cells: possible involvement of p38 MAP kinase. | 2002 Jul 31 |
1 |
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11304686 | Apoptosis induced by arsenic trioxide in leukemia U937 cells is dependent on activation of p38, inactivation of ERK and the Ca2+-dependent production of superoxide. | 2001 May 15 |
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