Cadmium

mitogen-activated protein kinase 1 ; Homo sapiens







63 Article(s)
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1 33297271 Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway. 2021 Jan 1
2 34580807 Cadmium affects autophagy in the human intestinal cells Caco-2 through ROS-mediated ERK activation. 2021 Sep 28 1
3 31860779 Zinc interference with Cd-induced hormetic effect in differentiated Caco-2 cells: Evidence for inhibition downstream ERK activation. 2020 Mar 1
4 32512071 Activation of the Erk/MAPK signaling pathway is a driver for cadmium induced prostate cancer. 2020 Aug 15 3
5 32512147 Cadmium exposure activates Akt/ERK Signaling and pro-inflammatory COX-2 expression in human gallbladder epithelial cells via a ROS dependent mechanism. 2020 Sep 1
6 33075233 Cadmium induces CCL2 production in glioblastoma cells via activation of MAPK, PI3K, and PKC pathways. 2020 Dec 1
7 30399392 Heterozygous huntingtin promotes cadmium neurotoxicity and neurodegeneration in striatal cells via altered metal transport and protein kinase C delta dependent oxidative stress and apoptosis signaling mechanisms. 2019 Jan 2
8 31410139 Cadmium induces A549 cell migration and invasion by activating ERK. 2019 Sep 6
9 31676320 Increasing ERK phosphorylation by inhibition of p38 activity protects against cadmium-induced apoptotic cell death through ERK/Drp1/p38 signaling axis in spermatocyte-derived GC-2spd cells. 2019 Dec 1 4
10 27940299 GPER/ERK&AKT/NF-κB pathway is involved in cadmium-induced proliferation, invasion and migration of GPER-positive thyroid cancer cells. 2017 Feb 15 4
11 28302721 Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure. 2017 May 12 1
12 29093498 Modeling cadmium-induced endothelial toxicity using human pluripotent stem cell-derived endothelial cells. 2017 Nov 1 1
13 29157834 16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells. 2017 Dec 1 1
14 26716417 Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. 2016 Feb 2 3
15 26751215 Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability. 2016 1
16 26782637 Cadmium induces mucin 8 expression via Toll-like receptor 4-mediated extracellular signal related kinase 1/2 and p38 mitogen-activated protein kinase in human airway epithelial cells. 2016 Jun 5
17 27071941 Arsenite and Cadmium Activate MAPK/ERK via Membrane Estrogen Receptors and G-Protein Coupled Estrogen Receptor Signaling in Human Lung Adenocarcinoma Cells. 2016 Jul 1
18 27466201 A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity. 2016 Sep 15 1
19 27558804 Pleiotropic roles of Ca+2/calmodulin-dependent pathways in regulating cadmium-induced toxicity in human osteoblast-like cell lines. 2016 Oct 17 4
20 25998312 Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 Pathways. 2015 3
21 26006730 Requirement of ERα and basal activities of EGFR and Src kinase in Cd-induced activation of MAPK/ERK pathway in human breast cancer MCF-7 cells. 2015 Aug 15 5
22 26248512 Calcium Signaling Involvement in Cadmium-Induced Astrocyte Cytotoxicity and Cell Death Through Activation of MAPK and PI3K/Akt Signaling Pathways. 2015 Sep 5
23 26385184 Cadmium promotes the proliferation of triple-negative breast cancer cells through EGFR-mediated cell cycle regulation. 2015 Nov 15 1
24 24824807 BNIP3 upregulation by ERK and JNK mediates cadmium-induced necrosis in neuronal cells. 2014 Aug 1 2
25 24973647 Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd²⁺-induced apoptosis. 2014 Sep 1
26 25069788 Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-κB, and AP-1 signaling pathways. 2014 Oct 3
27 23876460 Cadmium induces N-cadherin cleavage via ERK-mediated γ-secretase activation in C6 astroglia cells. 2013 Oct 24 6
28 21697648 Cadmium-induced apoptosis and necrosis in human osteoblasts: role of caspases and mitogen-activated protein kinases pathways. 2012 Feb 1
29 21984483 Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells. 2012 Jan 5
30 22019892 Cadmium exposure activates the ERK signaling pathway leading to altered osteoblast gene expression and apoptotic death in Saos-2 cells. 2012 Feb 6
31 22094458 An NF-κB-independent and Erk1/2-dependent mechanism controls CXCL8/IL-8 responses of airway epithelial cells to cadmium. 2012 Feb 2
32 23464422 Common docking domain mutation E322K of the ERK2 gene is infrequent in oral squamous cell carcinomas. 2012 2
33 21544200 Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network. 2011 Apr 22 2
34 19843171 ERK and cell death: cadmium toxicity, sustained ERK activation and cell death. 2010 Jan 5
35 20232314 Cadmium-induced hormetic effect in differentiated Caco-2 cells: ERK and p38 activation without cell proliferation stimulation. 2010 Jul 4
36 20554783 Pseudorabies virus tegument protein Us2 recruits the mitogen-activated protein kinase extracellular-regulated kinase (ERK) to membranes through interaction with the ERK common docking domain. 2010 Sep 1
37 19028507 Inhibition of benzopyrene-diol-epoxide (BPDE)-induced bax and caspase-9 by cadmium: role of mitogen activated protein kinase. 2009 Feb 10 2
38 19182378 Hwanggunchungyitang prevents cadmium-induced ototoxicity through suppression of the activation of caspase-9 and extracellular signal-related kinase in auditory HEI-OC1 cells. 2009 Feb 3
39 19220852 Long-term extracellular signal-related kinase activation following cadmium intoxication is negatively regulated by a protein kinase C-dependent pathway affecting cadmium transport. 2009 Mar 5
40 19327394 The role of MAPK in the biphasic dose-response phenomenon induced by cadmium and mercury in HEK293 cells. 2009 Jun 1
41 19333000 The cadmium-induced death of mesangial cells results in nephrotoxicity. 2009 May 2
42 19429262 NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells. 2009 Jun 22 1
43 19524565 Cadmium-induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway. 2009 Oct 2
44 19573589 Biphasic effect of cadmium on cell proliferation in human embryo lung fibroblast cells and its molecular mechanism. 2009 Sep 6
45 19817660 MAPK activation is involved in cadmium-induced Hsp70 expression in HepG2 cells. 2009 Oct 4
46 18021293 MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis. 2008 Apr 2
47 18703135 Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5. 2008 Oct 1 1
48 17367784 Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells. 2007 Apr 3 1
49 17479408 JWA gene is involved in cadmium-induced growth inhibition and apoptosis in HEK-293T cells. 2007 Jun 1
50 17485079 Induction of functional MT1 and MT2 isoforms by calcium in anaplastic thyroid carcinoma cells. 2007 May 29 2