Ceramides

mitogen-activated protein kinase 1 ; Homo sapiens







43 Article(s)
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1 35330102 Inhibition of Ceramide Glycosylation Enhances Cisplatin Sensitivity in Cholangiocarcinoma by Limiting the Activation of the ERK Signaling Pathway. 2022 Feb 28 1
2 33911565 Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth. 2019 Apr 1
3 28839270 A novel mechanism of ERK1/2 regulation in smooth muscle involving acetylation of the ERK1/2 scaffold IQGAP1. 2017 Aug 24 1
4 25576381 C6 ceramide dramatically enhances docetaxel-induced growth inhibition and apoptosis in cultured breast cancer cells: a mechanism study. 2015 Mar 1 1
5 26230734 Regulation of SREBPs by Sphingomyelin in Adipocytes via a Caveolin and Ras-ERK-MAPK-CREB Signaling Pathway. 2015 1
6 24997497 Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester-induced apoptosis in C6 glioma cells. 2014 Jul 5 1
7 25281403 Glucosylceramide synthase promotes Bcl-2 expression via the ERK signaling pathway in the K562/A02 leukemia drug-resistant cell line. 2014 Dec 1
8 23495037 Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol. 2013 Aug 3
9 23543151 Role of mitochondrial Bax, caspases, and MAPKs for ceramide-induced apoptosis in renal proximal tubular cells. 2013 Jul 1
10 22103431 Dissociation of ERK signalling inhibition from the anti-amyloidogenic action of synthetic ceramide analogues. 2012 May 1
11 19531467 Peptidoglycan induces cyclooxygenase-2 expression in macrophages by activating the neutral sphingomyelinase-ceramide pathway. 2009 Jul 31 1
12 18623086 Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway. 2008 Sep 15 2
13 16261164 Laser microdissection and microarray analysis of breast tumors reveal ER-alpha related genes and pathways. 2006 Mar 2 1
14 16969513 Paclitaxel and ceramide synergistically induce cell death with transient activation of EGFR and ERK pathway in pancreatic cancer cells. 2006 Oct 4
15 17030510 Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK. 2006 Dec 1 3
16 15781658 Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species. 2005 Mar 15 1
17 16106045 Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1beta in hepatocytes. 2005 Nov 1
18 16290312 IGF-I protects cortical neurons against ceramide-induced apoptosis via activation of the PI-3K/Akt and ERK pathways; is this protection independent of CREB and Bcl-2? 2005 Dec 14 1
19 12738796 Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors. 2003 Jul 18 2
20 14713309 Ceramide pathways modulate ethanol-induced cell death in astrocytes. 2003 Dec 2
21 12034359 Delayed ERK activation by ceramide reduces melanin synthesis in human melanocytes. 2002 Sep 1
22 12220618 C(2)-ceramide-induced circular smooth muscle cell contraction involves PKC-epsilon and p44/p42 MAPK activation in cat oesophagus. Mitogen-activated protein kinase. 2002 Nov 1
23 12435806 Mechanism of extracellular signal-regulated kinase activation by the CB(1) cannabinoid receptor. 2002 Dec 1
24 11350735 Inhibitory actions of ceramide upon PKC-epsilon/ERK interactions. 2001 Jun 9
25 11422444 Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation. 2001 Jun 1
26 11675379 Tumor necrosis factor-alpha supports the survival of osteoclasts through the activation of Akt and ERK. 2001 Dec 28 1
27 10671221 Conversion of p56(lck) to p60(lck) in human peripheral blood T lymphocytes is dependent on co- stimulation through accessory receptors: involvement of phospholipase C, protein kinase C and MAP-kinases in vivo. 2000 Feb 1
28 10926924 Activation of extracellular signal-regulated kinase 1/2 inhibits type I collagen expression by human skin fibroblasts. 2000 Nov 3 2
29 11053253 De novo-synthesized ceramide signals apoptosis in astrocytes via extracellular signal-regulated kinase. 2000 Nov 4
30 11062012 Ceramide induction of COX-2 and PGE(2) in pulmonary A549 cells does not involve activation of NF-kappaB. 2000 Nov 2 3
31 9478967 Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. 1998 Feb 27 2
32 9668339 Sphingosine-1-phosphate in cell growth and cell death. 1998 Jun 19 1
33 9736250 Identification of ceramide targets in interleukin-1 and tumor necrosis factor-alpha signaling in mesangial cells. 1998 Sep 2
34 9830045 Ceramide regulates the transcription of cyclooxygenase-2. Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways. 1998 Dec 4 3
35 9884018 Oxidant-mediated activation of mitogen-activated protein kinases and nuclear transcription factors in the cardiovascular system: a brief overview. 1998 Nov 2
36 12671299 Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis. The role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis. 1998 Jun 1
37 9144515 Mitogen-activated protein kinase activation during IgG-dependent phagocytosis in human neutrophils: inhibition by ceramide. 1997 May 15 1
38 9354428 Activated Ki-ras enhances sensitivity of ceramide-induced apoptosis without c-Jun NH2-terminal kinase/stress-activated protein kinase or extracellular signal-regulated kinase activation in human colon cancer cells. 1997 Nov 1 2
39 9415703 Coordinate regulation of stress- and mitogen-activated protein kinases in the apoptotic actions of ceramide and sphingosine. 1997 Dec 1
40 8645177 The differential regulation of cyclic AMP by sphingomyelin-derived lipids and the modulation of sphingolipid-stimulated extracellular signal regulated kinase-2 in airway smooth muscle. 1996 May 1 3
41 8647130 Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle. 1996 May 1 2
42 8662702 Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades. 1996 May 31 2
43 8950029 Effects of Ara-C on neutral sphingomyelinase and mitogen- and stress-activated protein kinases in T-lymphocyte cell lines. 1996 Nov 1