Oxygen

mitogen-activated protein kinase 1 ; Homo sapiens







26 Article(s)
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1 34898379 Hyperoxia induces alveolar epithelial cell apoptosis by regulating mitochondrial function through small mothers against decapentaplegic 3 (SMAD3) and extracellular signal-regulated kinase 1/2 (ERK1/2). 2022 Jan 1
2 34388291 ERK signaling controls productive HIF-1 binding to chromatin and cancer cell adaptation to hypoxia through HIF-1α interaction with NPM1. 2021 Dec 1
3 32409654 Cuprous oxide nanoparticles trigger reactive oxygen species-induced apoptosis through activation of erk-dependent autophagy in bladder cancer. 2020 May 14 2
4 32806555 MDM2 Antagonists Induce a Paradoxical Activation of Erk1/2 through a P53-Dependent Mechanism in Dedifferentiated Liposarcomas: Implications for Combinatorial Strategies. 2020 Aug 12 1
5 30535970 HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia. 2019 Feb 1
6 31137604 Hypoxia-Induced Epithelial-To-Mesenchymal Transition Mediates Fibroblast Abnormalities via ERK Activation in Cutaneous Wound Healing. 2019 May 24 1
7 31551405 Basic Fibroblast Growth Factor Reduces Permeability and Apoptosis of Human Brain Microvascular Endothelial Cells in Response to Oxygen and Glucose Deprivation Followed by Reoxygenation via the Fibroblast Growth Factor Receptor 1 (FGFR1)/ERK Pathway. 2019 Sep 25 1
8 29222974 Cold atmospheric plasma (CAP), a novel physicochemical source, induces neural differentiation through cross-talk between the specific RONS cascade and Trk/Ras/ERK signaling pathway. 2018 Feb 1
9 27909249 Mortalin-mediated and ERK-controlled targeting of HIF-1α to mitochondria confers resistance to apoptosis under hypoxia. 2017 Jan 15 1
10 28115238 NGF protects against oxygen and glucose deprivation-induced oxidative stress and apoptosis by up-regulation of HO-1 through MEK/ERK pathway. 2017 Feb 22 1
11 27637085 Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A. 2016 Oct 18 1
12 25002363 Activation of adenosine A2B receptor impairs properties of trophoblast cells and involves mitogen-activated protein (MAP) kinase signaling. 2014 Sep 1
13 23281060 Zn2+ -induced ERK activation mediates PARP-1-dependent ischemic-reoxygenation damage to oligodendrocytes. 2013 Mar 1
14 23348708 p38 Mitogen-activated protein kinase and extracellular signal-regulated kinase signaling pathways are not essential regulators of formyl peptide-stimulated p47(phox) activation in neutrophils. 2013 Feb 15 1
15 23478801 Neuroglobin, a novel intracellular hexa-coordinated globin, functions as a tumor suppressor in hepatocellular carcinoma via Raf/MAPK/Erk. 2013 May 2
16 22335456 Purine nucleosides: endogenous neuroprotectants in hypoxic brain. 2012 May 1
17 21510275 Different activation of ERK1/2 and p38 with hyperbaric oxygen in dorsal root ganglion. 2011 Mar-Apr 8
18 17704189 Constitutive NADPH oxidase and increased mitochondrial respiratory chain activity regulate chemokine gene expression. 2007 Nov 1
19 16328781 Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells. 2006 Jan 1
20 16849472 Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1. 2006 Aug 1 1
21 15743827 Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: role of p47phox phosphorylation and binding to TRAF4. 2005 Mar 2
22 16103078 A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma. 2005 Aug 15 1
23 15181371 Epsilon protein kinase C mediated ischemic tolerance requires activation of the extracellular regulated kinase pathway in the organotypic hippocampal slice. 2004 Jun 1
24 15336911 Role of defective ERK phosphorylation in the impaired GM-CSF-induced oxidative response of neutrophils in elderly humans. 2004 Aug 1
25 15453987 Oxygen free radical-dependent activation of extracellular signal-regulated kinase mediates apoptosis-like cell death after traumatic brain injury. 2004 Sep 1
26 7923153 Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2). 1994 Oct 15 1