Acetylcysteine

mitogen-activated protein kinase 1 ; Homo sapiens







94 Article(s)
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1 33748286 ROS-ERK Pathway as Dual Mediators of Cellular Injury and Autophagy-Associated Adaptive Response in Urinary Protein-Irritated Renal Tubular Epithelial Cells. 2021 1
2 34475984 Anti-proliferative, pro-apoptotic and anti-invasive effect of the copper coordination compound Cas III-La through the induction of reactive oxygen species and regulation of Wnt/β-catenin pathway in glioma. 2021 1
3 31698002 N-acetyl-l-cysteine protects porcine oocytes undergoing meiotic resumption from heat stress. 2020 Jan 2
4 32512147 Cadmium exposure activates Akt/ERK Signaling and pro-inflammatory COX-2 expression in human gallbladder epithelial cells via a ROS dependent mechanism. 2020 Sep 2
5 32736702 Activation of ERK1/2-mTORC1-NOX4 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in retinal pigment epithelial cells. 2020 Aug 27 1
6 32745510 Fine particulate matter reduces the pluripotency and proliferation of human embryonic stem cells through ROS induced AKT and ERK signaling pathway. 2020 Sep 2
7 30677238 Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway. 2019 May 1
8 31127990 Effect of TGF-β1 on Apoptosis of Colon Cancer Cells Via the ERK Signaling Pathway. 2019 Mar-Apr 2
9 31360690 Ajoene, a Major Organosulfide Found in Crushed Garlic, Induces NAD(P)H:quinone Oxidoreductase Expression Through Nuclear Factor E2-related Factor-2 Activation in Human Breast Epithelial Cells. 2019 Jun 2
10 31386885 Xanthohumol exhibits anti-myeloma activity in vitro through inhibition of cell proliferation, induction of apoptosis via the ERK and JNK-dependent mechanism, and suppression of sIL-6R and VEGF production. 2019 Nov 2
11 29326072 Novel 1,4-naphthoquinone derivatives induce apoptosis via ROS-mediated p38/MAPK, Akt and STAT3 signaling in human hepatoma Hep3B cells. 2018 Mar 1
12 29479036 Arsenite exposure potentiates apoptosis-inducing effects of tumor necrosis factor-alpha- through reactive oxygen species. 2018 1
13 29510199 Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways. 2018 Apr 15 1
14 29799741 Combination of Selenomethionine and N-Acetylcysteine Alleviates the Joint Toxicities of Aflatoxin B1 and Ochratoxin A by ERK MAPK Signal Pathway in Porcine Alveolar Macrophages. 2018 Jun 13 1
15 29960031 A new xanthatin analogue 1β-hydroxyl-5α-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma. 2018 Sep 2
16 30055241 Promotion of SIRT1 protein degradation and lower SIRT1 gene expression via reactive oxygen species is involved in Sb-induced apoptosis in BEAS-2b cells. 2018 Oct 15 1
17 28087840 Vibrio cholerae Cholix Toxin-Induced HepG2 Cell Death is Enhanced by Tumor Necrosis Factor-Alpha Through ROS and Intracellular Signal-Regulated Kinases. 2017 Apr 1 2
18 28178193 Cearoin Induces Autophagy, ERK Activation and Apoptosis via ROS Generation in SH-SY5Y Neuroblastoma Cells. 2017 Feb 6 1
19 28583366 Pentoxifylline induces apoptosis of HepG2 cells by reducing reactive oxygen species production and activating the MAPK signaling. 2017 Aug 15 1
20 26320741 The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes. 2016 Nov 1
21 26718128 Hispolon inhibits breast cancer cell migration by reversal of epithelial-to-mesenchymal transition via suppressing the ROS/ERK/Slug/E-cadherin pathway. 2016 Feb 1
22 26808296 Helicobacter pylori induces Snail expression through ROS-mediated activation of Erk and inactivation of GSK-3β in human gastric cancer cells. 2016 Dec 1
23 27058530 Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals. 2016 Apr 6 1
24 27484511 Aromatic heterocyclic esters of podophyllotoxin exert anti-MDR activity in human leukemia K562/ADR cells via ROS/MAPK signaling pathways. 2016 Nov 10 1
25 27572503 Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-κB pathway. 2016 Oct 1
26 27941930 ERK-mediated NF-κB activation through ASIC1 in response to acidosis. 2016 Dec 12 1
27 23836369 Activation of MAPK pathways and downstream transcription factors in 2-aminobiphenyl-induced apoptosis. 2015 Feb 1
28 25138434 Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft. 2015 Jul 1
29 25527729 Effect of silver nanoparticles on mitogen-activated protein kinases activation: role of reactive oxygen species and implication in DNA damage. 2015 Jan 1
30 26043815 Lipoic acid and N-acetylcysteine prevent ammonia-induced inflammatory response in C6 astroglial cells: The putative role of ERK and HO1 signaling pathways. 2015 Oct 1
31 26100173 Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells. 2015 Jul 1
32 24586814 The pentachlorophenol metabolite tetrachlorohydroquinone induces massive ROS and prolonged p-ERK expression in splenocytes, leading to inhibition of apoptosis and necrotic cell death. 2014 2
33 24973647 Redox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd²⁺-induced apoptosis. 2014 Sep 1
34 23416263 Cerium oxide nanoparticles induce cytotoxicity in human hepatoma SMMC-7721 cells via oxidative stress and the activation of MAPK signaling pathways. 2013 Apr 2
35 23433299 Grape seed extract triggers apoptosis in Caco-2 human colon cancer cells through reactive oxygen species and calcium increase: extracellular signal-regulated kinase involvement. 2013 Sep 14 1
36 23490067 Arachidonic acid enhances TPA-induced differentiation in human leukemia HL-60 cells via reactive oxygen species-dependent ERK activation. 2013 Apr 1
37 24001789 ZnO nanoparticles induce TNF-α expression via ROS-ERK-Egr-1 pathway in human keratinocytes. 2013 Dec 2
38 24273890 The synergistic antitumor activity of arsenic trioxide and vitamin K2 in HL-60 cells involves increased ROS generation and regulation of the ROS-dependent MAPK signaling pathway. 2013 Oct 1
39 22824464 NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway. 2012 Sep 15 2
40 22867088 Glutathione-S-transferase M1 regulation of diesel exhaust particle-induced pro-inflammatory mediator expression in normal human bronchial epithelial cells. 2012 Aug 6 1
41 22878643 The adenosine A3 receptor agonist Cl-IB-MECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells. 2012 Dec 2
42 20868662 The cytotoxic mechanism of malondialdehyde and protective effect of carnosine via protein cross-linking/mitochondrial dysfunction/reactive oxygen species/MAPK pathway in neurons. 2011 Jan 10 3
43 21055460 Suppression of human prostate cancer PC-3 cell growth by N-acetylcysteine involves over-expression of Cyr61. 2011 Feb 1
44 21093414 Snail-mediated regulation of reactive oxygen species in ARCaP human prostate cancer cells. 2011 Jan 7 1
45 21453688 Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells. 2011 Aug 15 1
46 21833842 Carnosic acid, a rosemary phenolic compound, induces apoptosis through reactive oxygen species-mediated p38 activation in human neuroblastoma IMR-32 cells. 2011 Dec 1
47 21980400 PI3K and ERK-induced Rac1 activation mediates hypoxia-induced HIF-1α expression in MCF-7 breast cancer cells. 2011 1
48 20402656 Cytotoxicity of a vanadyl(IV) complex with a multidentate oxygen donor in osteoblast cell lines in culture. 2010 Jan 2
49 20432471 Caffeine induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-fos pathway and activation of p38 MAPK/c-jun pathway. 2010 Sep 1
50 20443032 Vanadium compounds discriminate hepatoma and normal hepatic cells by differential regulation of reactive oxygen species. 2010 Sep 2