Prostaglandins E

mitogen-activated protein kinase 1 ; Homo sapiens







33 Article(s)
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1 19804834 Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. 2010 Jan 2
2 20015475 Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK. 2010 Feb 6
3 20093341 Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. 2010 Apr 2
4 20381235 Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: an update on the molecular mechanisms. 2010 Sep 1 2
5 19299454 Up-regulation of cyclooxygenase-2 expression and prostaglandin E2 production in human endometriotic cells by macrophage migration inhibitory factor: involvement of novel kinase signaling pathways. 2009 Jul 2
6 19371268 COX-2 and iNOS are critical in advanced glycation end product-activated chondrocytes in vitro. 2009 May 1
7 19558494 Inhibition of 12-LOX and COX-2 reduces the proliferation of human epidermoid carcinoma cells (A431) by modulating the ERK and PI3K-Akt signalling pathways. 2009 Nov 1
8 19623651 Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells. 2009 Dec 1 3
9 19881225 Proteinase-activated receptor-2-triggered prostaglandin E(2) release, but not cyclooxygenase-2 upregulation, requires activation of the phosphatidylinositol 3-kinase/Akt / nuclear factor-kappaB pathway in human alveolar epithelial cells. 2009 Nov 1
10 17708577 Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells. 2008 Mar-Apr 1
11 18271757 Prostaglandin E1 inhibits IL-6-induced MCP-1 expression by interfering specifically in IL-6-dependent ERK1/2, but not STAT3, activation. 2008 May 15 1
12 18285354 Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes. 2008 Apr 3
13 18583546 E series of prostaglandin receptor 2-mediated activation of extracellular signal-regulated kinase/activator protein-1 signaling is required for the mitogenic action of prostaglandin E2 in esophageal squamous-cell carcinoma. 2008 Oct 4
14 18622047 Src kinase-mediated parallel activation of prostaglandin and constitutive nitric oxide synthase pathways in leptin protection of gastric mucosa against ethanol cytotoxicity. 2008 Jun 1
15 17031853 Prostaglandin E2 downregulates TNF-alpha-induced production of matrix metalloproteinase-1 in HCS-2/8 chondrocytes by inhibiting Raf-1/MEK/ERK cascade through EP4 prostanoid receptor activation. 2007 Feb 15 2
16 17604021 Signal transduction pathways for epidermal growth factor stimulated cyclooxygenase-2 induction in astrocytes. 2007 Aug 2
17 17699671 Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21. 2007 Aug 15 4
18 17875734 Prostaglandin E(2) induces breast cancer related aromatase promoters via activation of p38 and c-Jun NH(2)-terminal kinase in adipose fibroblasts. 2007 Sep 15 2
19 16204467 EP(4) prostanoid receptor coupling to a pertussis toxin-sensitive inhibitory G protein. 2006 Jan 2
20 16427328 Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. 2006 May 1
21 16458997 Hypoxia-induced remodelling of PDE4 isoform expression and cAMP handling in human pulmonary artery smooth muscle cells. 2006 Jul 1
22 17085321 Concomitant activation of extracellular signal-regulated kinase and induction of COX-2 stimulates maximum prostaglandin E2 synthesis in human airway epithelial cells. 2006 Dec 2
23 16081678 Prostaglandin E2 enhances neurotrophin-4 production via EP3 receptor in human keratinocytes. 2005 Nov 3
24 15170913 Activation of synovial cell p38 MAP kinase by macrophage migration inhibitory factor. 2004 Jun 1
25 15345332 Activation of osteoblastic functions by a mediator of pain, bradykinin. 2004 Oct 1 1
26 15492268 Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2. 2004 Oct 15 1
27 12493746 Differentiation status-dependent regulation of cyclooxygenase-2 expression and prostaglandin E2 production by epidermal growth factor via mitogen-activated protein kinase in articular chondrocytes. 2003 Mar 14 1
28 12727858 Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1. 2003 May 1 3
29 12730964 Oncostatin M enhances the expression of prostaglandin E2 and cyclooxygenase-2 in astrocytes: synergy with interleukin-1beta, tumor necrosis factor-alpha, and bacterial lipopolysaccharide. 2003 Jun 1
30 14634122 Cyclooxygenase-2-derived E prostaglandins down-regulate matrix metalloproteinase-1 expression in fibroblast-like synoviocytes via inhibition of extracellular signal-regulated kinase activation. 2003 Dec 1 7
31 12096032 Molecular mechanisms of lipopolysaccharide-induced cyclooxygenase-2 expression in human neutrophils: involvement of the mitogen-activated protein kinase pathway and regulation by anti-inflammatory cytokines. 2002 Jul 2
32 11290527 ERK activation and mitogenesis in human airway smooth muscle cells. 2001 May 1
33 10564179 Role of ERK MAP kinases in responses of cultured human airway smooth muscle cells to IL-1beta. 1999 Nov 1