Tretinoin

mitogen-activated protein kinase 1 ; Homo sapiens







75 Article(s)
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1 34058077 Crosstalk between hnRNP K and SET in ATRA-induced differentiation in acute promyelocytic leukemia. 2021 Jul 1
2 34579932 Expression of concern: "Tyrosine phosphatase inhibitors combined with retinoic acid can enhance differentiation of neuroblastoma cells and trigger ERK- and AKT-dependent, p53-independent senescence" Cancer Letters, Volume 328, Issue 1, 1 January 2013, Pages 44-54. 2021 Nov 28 1
3 32630207 All-Trans Retinoic Acid Enhances both the Signaling for Priming and the Glycolysis for Activation of NLRP3 Inflammasome in Human Macrophage. 2020 Jul 1 1
4 32882760 All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells. 2020 Sep 1
5 33088261 Willin/FRMD6 Influences Mechanical Phenotype and Neuronal Differentiation in Mammalian Cells by Regulating ERK1/2 Activity. 2020 4
6 30576481 Inhibition of protein phosphatase PPM1D enhances retinoic acid-induced differentiation in human embryonic carcinoma cell line. 2019 Jun 1 2
7 30709899 Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid. 2019 Apr 2
8 30859584 RA promotes proliferation of primordial germ cell-like cells differentiated from porcine skin-derived stem cells. 2019 Aug 4
9 31218101 Combination of enzastaurin and ATRA exerts dose-dependent dual effects on ATRA-resistant acute promyelocytic leukemia cells. 2019 1
10 29434845 All-trans retinoic acid inhibits the proliferation of SGC7901 cells by regulating caveolin-1 localization via the ERK/MAPK signaling pathway. 2018 Feb 10
11 29772445 The protective role of all-transretinoic acid (ATRA) against colorectal cancer development is achieved via increasing miR-3666 expression and decreasing E2F7 expression. 2018 Aug 6
12 29166739 [Study of the effects and mechanism of all-trans retinoic acid on leukemic cell line U937 cells with NPM1 mutation]. 2017 Oct 14 2
13 27074819 The HER2 inhibitor TAK165 Sensitizes Human Acute Myeloid Leukemia Cells to Retinoic Acid-Induced Myeloid Differentiation by activating MEK/ERK mediated RARα/STAT1 axis. 2016 Apr 14 1
14 27101150 RAF-1/MEK/ERK pathway regulates ATRA-induced differentiation in acute promyelocytic leukemia cells through C/EBPβ, C/EBPε and PU.1. 2016 Jun 4
15 27665842 Staurosporine enhances ATRA-induced granulocytic differentiation in human leukemia U937 cells via the MEK/ERK signaling pathway. 2016 Nov 2
16 27919568 All-trans retinoic acid suppresses the adhering ability of ARPE-19 cells via mitogen-activated protein kinase and focal adhesion kinase. 2016 Dec 1
17 25343668 Retinoic acid modulates interferon-γ production by hepatic natural killer T cells via phosphatase 2A and the extracellular signal-regulated kinase pathway. 2015 Mar 3
18 25485998 Effects of hyperoxic exposure on signal transduction pathways in the lung. 2015 Apr 1
19 26557664 All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism. 2015 3
20 24335929 Metabolomic and network analysis of pharmacotherapies for sensorineural hearing loss. 2014 Jan 1
21 24769642 Combined staurosporine and retinoic acid induces differentiation in retinoic acid resistant acute promyelocytic leukemia cell lines. 2014 Apr 28 1
22 24894398 Inhibition by all-trans-retinoic acid of transforming growth factor-β-induced collagen gel contraction mediated by human tenon fibroblasts. 2014 Jun 3 2
23 24959884 Nuclear MEK1 sequesters PPARγ and bisects MEK1/ERK signaling: a non-canonical pathway of retinoic acid inhibition of adipocyte differentiation. 2014 1
24 25446614 Compounds blocking methylglyoxal-induced protein modification and brain endothelial injury. 2014 Nov 1
25 22982089 Cellular retinoic acid binding protein I mediates rapid non-canonical activation of ERK1/2 by all-trans retinoic acid. 2013 Jan 1
26 23022267 Tyrosine phosphatase inhibitors combined with retinoic acid can enhance differentiation of neuroblastoma cells and trigger ERK- and AKT-dependent, p53-independent senescence. 2013 Jan 1 1
27 23142153 Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway. 2013 Jan 1
28 23396089 Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells. 2013 Apr 1 1
29 23554907 The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells. 2013 1
30 23656719 6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. 2013 May 9 2
31 23877261 Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid. 2013 Oct 1
32 24004656 Importance of ERK activation in As2O3-induced differentiation and promyelocytic leukemia nuclear bodies formation in neuroblastoma cells. 2013 Nov 1
33 22182854 Src inhibitors, PP2 and dasatinib, increase retinoic acid-induced association of Lyn and c-Raf (S259) and enhance MAPK-dependent differentiation of myeloid leukemia cells. 2012 Jun 1
34 22766505 PI3K/AKT and ERK regulate retinoic acid-induced neuroblastoma cellular differentiation. 2012 Aug 3 1
35 21252119 ATRA activates and PDGF-BB represses the SM22α promoter through KLF4 binding to, or dissociating from, its cis-DNA elements. 2011 Jun 1 1
36 21740303 Interferon regulatory factor-1 binds c-Cbl, enhances mitogen activated protein kinase signaling and promotes retinoic acid-induced differentiation of HL-60 human myelo-monoblastic leukemia cells. 2011 Dec 1
37 20060826 Up- or downregulation of tescalcin in HL-60 cells is associated with their differentiation to either granulocytic or macrophage-like lineage. 2010 Apr 15 1
38 20615082 Arsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells. 2010 Sep 1
39 20844755 Serum free cultured bone marrow mesenchymal stem cells as a platform to characterize the effects of specific molecules. 2010 Sep 10 2
40 19127080 Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells. 2009 2
41 19204783 HDAC3 as a molecular chaperone for shuttling phosphorylated TR2 to PML: a novel deacetylase activity-independent function of HDAC3. 2009 4
42 17949889 Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors. 2008 Jan 1
43 18006504 A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. 2008 Feb 15 13
44 18064629 All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes. 2008 May 1
45 18636178 Nicotinamide attenuates aquaporin 3 overexpression induced by retinoic acid through inhibition of EGFR/ERK in cultured human skin keratinocytes. 2008 Aug 6
46 18682553 Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. 2008 Aug 12 4
47 18724384 Differential enhancement of leukaemia cell differentiation without elevation of intracellular calcium by plant-derived sesquiterpene lactone compounds. 2008 Nov 1
48 18989765 Effects of all-trans retinoic acid on Th1- and Th2-related chemokines production in monocytes. 2008 Dec 4
49 19099631 [Effect of mitogen-activated protein kinases on ATRA-induced differentiation of NB4 cells]. 2008 Dec 13
50 17182884 Retinoic acid inhibits HIV-1-induced podocyte proliferation through the cAMP pathway. 2007 Jan 1