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heat shock protein 90 alpha family class A member 1 ; Homo sapiens







24 Article(s)
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1 35056725 Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1H)-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90. 2022 Jan 9 1
2 35429283 Design, synthesis, and biological evaluation of 4-(1H-1,2,3-triazol-1-yl)benzamides as HSP90 inhibitors. 2022 Apr 16 1
3 34286666 In silico identification of potential Hsp90 inhibitors via ensemble docking, DFT and molecular dynamics simulations. 2021 Jul 21 1
4 34770993 Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90. 2021 Oct 30 2
5 31560152 Understanding conformational diversity of heat shock protein 90 (HSP90) and binding features of inhibitors to HSP90 via molecular dynamics simulations. 2020 Jan 1
6 32527460 Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting. 2020 Aug 1 1
7 32812680 Hsp90 chaperones have an energetic hot-spot for binding inhibitors. 2020 Oct 4
8 30827868 Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents. 2019 Apr 1 1
9 30869872 The Hsp90 Chaperone: 1H and 19F Dynamic Nuclear Magnetic Resonance Spectroscopy Reveals a Perfect Enzyme. 2019 Apr 9 2
10 31141217 Structures of Hsp90α and Hsp90β bound to a purine-scaffold inhibitor reveal an exploitable residue for drug selectivity. 2019 Oct 1
11 31493740 Natural compounds as potential Hsp90 inhibitors for breast cancer-Pharmacophore guided molecular modelling studies. 2019 Dec 1
12 31518867 Synthesis, characterization, anti-tumor activity, photo-luminescence and BHb/HHb/Hsp90 molecular docking of zinc(II) hydroxyl-terpyridine complexes. 2019 Dec 2
13 31725288 Discovery of Novel Celastrol Derivatives as Hsp90-Cdc37 Interaction Disruptors with Antitumor Activity. 2019 Dec 12 1
14 29564982 Towards the In-silico Design of New HSP90 Inhibitors: Molecular Docking and 3D-QSAR CoMFA Studies of Tetrahydropyrido [4, 3-d] Pyrimidine Derivatives as HSP90 Inhibitors. 2018 1
15 28426997 Design and synthesis of neolamellarin a derivatives targeting heat shock protein 90. 2017 Jul 28 1
16 26056257 Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90. 2015 Jun 23 1
17 26100249 Curcumin inhibits human cytomegalovirus by downregulating heat shock protein 90. 2015 Sep 1
18 24726919 Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone. 2014 Jun 12 1
19 20146531 Insights into the conformational dynamics of the E3 ubiquitin ligase CHIP in complex with chaperones and E2 enzymes. 2010 Mar 16 1
20 20373211 Molecular modelling and docking studies on heat shock protein 90 (Hsp90) inhibitors. 2010 Jan 1 1
21 17764690 Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs. 2007 Oct 5 2
22 16565516 Localization of sites of interaction between p23 and Hsp90 in solution. 2006 May 19 1
23 15713410 Crystal structures of human HSP90alpha-complexed with dihydroxyphenylpyrazoles. 2005 Mar 1 1
24 16165354 Structure-based design of 7-carbamate analogs of geldanamycin. 2005 Nov 15 1