| 1 |
35388292 | HSP90 Inhibitors Modulate SARS-CoV-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation and Barrier Dysfunction. | 2022 |
1 |
| 2 |
35463341 | A Low Membrane Hsp70 Expression in Tumor Cells With Impaired Lactate Metabolism Mediates Radiosensitization by NVP-AUY922. | 2022 |
1 |
| 3 |
33743824 | Cooperative treatment effectiveness of ATR and HSP90 inhibition in Ewing's sarcoma cells. | 2021 Mar 20 |
1 |
| 4 |
34199261 | The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction. | 2021 Jun 13 |
2 |
| 5 |
34301262 | AUY922 induces retinal toxicity through attenuating TRPM1. | 2021 Jul 23 |
2 |
| 6 |
34607394 | Integrin αvβ3 Induces HSP90 Inhibitor Resistance via FAK Activation in KRAS-Mutant Non-Small Cell Lung Cancer. | 2021 Sep 30 |
1 |
| 7 |
34612127 | HSP90 inhibition acts synergistically with heat to induce a pro-immunogenic form of cell death in colon cancer cells. | 2021 |
1 |
| 8 |
32037409 | Optimized HSP90 mediated fluorescent probes for cancer-specific bioimaging. | 2020 Mar 4 |
2 |
| 9 |
32669400 | Fatty Acid Oxidation Is an Adaptive Survival Pathway Induced in Prostate Tumors by HSP90 Inhibition. | 2020 Oct |
1 |
| 10 |
32683166 | Fluoropyrimidin-2,4-dihydroxy-5-isopropylbenzamides as antitumor agents against CRC and NSCLC cancer cells. | 2020 Oct 1 |
1 |
| 11 |
32722485 | HSP90 Inhibition and Modulation of the Proteome: Therapeutical Implications for Idiopathic Pulmonary Fibrosis (IPF). | 2020 Jul 25 |
1 |
| 12 |
32768937 | Low dose HSP90 inhibition with AUY922 blunts rapid evolution of metastatic and drug resistant phenotypes induced by TGF-β and paclitaxel in A549 cells. | 2020 Sep |
3 |
| 13 |
32903557 | Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors. | 2020 |
1 |
| 14 |
33109551 | Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells. | 2020 Nov |
1 |
| 15 |
30488605 | Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma. | 2019 May 15 |
3 |
| 16 |
30980109 | Chaperone-mediated autophagy degradation of IGF-1Rβ induced by NVP-AUY922 in pancreatic cancer. | 2019 Sep |
1 |
| 17 |
31561045 | Discovery of 2-isoxazol-3-yl-acetamide analogues as heat shock protein 90 (HSP90) inhibitors with significant anti-HIV activity. | 2019 Dec 1 |
1 |
| 18 |
31569342 | Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922. | 2019 Sep 28 |
4 |
| 19 |
31684108 | Gene Expression Signature-Based Approach Identifies Antifungal Drug Ciclopirox As a Novel Inhibitor of HMGA2 in Colorectal Cancer. | 2019 Nov 2 |
1 |
| 20 |
29247830 | Phase 2 Study of the HSP-90 Inhibitor AUY922 in Previously Treated and Molecularly Defined Patients with Advanced Non-Small Cell Lung Cancer. | 2018 Apr |
1 |
| 21 |
29396630 | The HSP90 inhibitor NVP-AUY922 inhibits growth of HER2 positive and trastuzumab-resistant breast cancer cells. | 2018 Aug |
1 |
| 22 |
29437790 | HER3-Mediated Resistance to Hsp90 Inhibition Detected in Breast Cancer Xenografts by Affibody-Based PET Imaging. | 2018 Apr 15 |
1 |
| 23 |
30154228 | EGFR Exon 20 Insertion Mutations Display Sensitivity to Hsp90 Inhibition in Preclinical Models and Lung Adenocarcinomas. | 2018 Dec 15 |
3 |
| 24 |
30351341 | Activity of the Hsp90 inhibitor luminespib among non-small-cell lung cancers harboring EGFR exon 20 insertions. | 2018 Oct 1 |
2 |
| 25 |
28139075 | How Selective are Hsp90 Inhibitors for Cancer Cells over Normal Cells? | 2017 Mar 7 |
8 |
| 26 |
28143445 | HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation. | 2017 Jan 31 |
1 |
| 27 |
28298630 | Proteomic analysis of proteome and histone post-translational modifications in heat shock protein 90 inhibition-mediated bladder cancer therapeutics. | 2017 Mar 15 |
1 |
| 28 |
28301080 | HSP90 inhibitor AUY922 can reverse Fulvestrant induced feedback reaction in human breast cancer cells. | 2017 Jun |
1 |
| 29 |
28412368 | HSP90 inhibitor NVP-AUY922 induces cell apoptosis by disruption of the survivin in papillary thyroid carcinoma cells. | 2017 May 27 |
1 |
| 30 |
28664723 | Delivery and Release of Small-Molecule Probes in Mitochondria Using Traceless Linkers. | 2017 Jul 19 |
1 |
| 31 |
28779264 | Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition. | 2017 Oct |
1 |
| 32 |
28797845 | The HSP90 inhibitor, NVP-AUY922, attenuates intrinsic PI3K inhibitor resistance in KRAS-mutant non-small cell lung cancer. | 2017 Oct 10 |
2 |
| 33 |
28987383 | HSP90 inhibitor (NVP-AUY922) enhances the anti-cancer effect of BCL-2 inhibitor (ABT-737) in small cell lung cancer expressing BCL-2. | 2017 Dec 28 |
1 |
| 34 |
26604096 | Bioluminescence Imaging to Monitor the Effects of the Hsp90 Inhibitor NVP-AUY922 on NF-κB Pathway in Endometrial Cancer. | 2016 Aug |
1 |
| 35 |
26723875 | The HSP90 inhibitor, NVP-AUY922, sensitizes KRAS-mutant non-small cell lung cancer with intrinsic resistance to MEK inhibitor, trametinib. | 2016 Mar 1 |
1 |
| 36 |
26748184 | The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo. | 2016 Jan 15 |
2 |
| 37 |
27129177 | Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2-positive breast cancer patients who have progressed on trastuzumab-based regimen. | 2016 Jun 21 |
1 |
| 38 |
27347156 | Efficiency of AUY922 in mice with adult T-cell leukemia/lymphoma. | 2016 Jul |
1 |
| 39 |
27379708 | A Phase 2 Study of the Hsp90 Inhibitor AUY922 as Treatment for Patients with Refractory Gastrointestinal Stromal Tumors. | 2016 Jul 2 |
3 |
| 40 |
27391062 | Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. | 2016 Aug 2 |
1 |
| 41 |
27422303 | A phase II study of the HSP90 inhibitor AUY922 in chemotherapy refractory advanced pancreatic cancer. | 2016 Sep |
1 |
| 42 |
27551334 | Combination of JAK2 and HSP90 inhibitors: an effective therapeutic option in drug-resistant chronic myelogenous leukemia. | 2016 May |
1 |
| 43 |
25389633 | Novel heat shock protein 90 inhibitor NVP-AUY922 synergizes with the histone deacetylase inhibitor PXD101 in induction of death of anaplastic thyroid carcinoma cells. | 2015 Feb |
1 |
| 44 |
25820332 | Experience with HSP90 inhibitor AUY922 in patients with relapsed or refractory non-Hodgkin lymphoma. | 2015 Jul |
1 |
| 45 |
25821558 | HSP90 inhibitor AUY922 induces cell death by disruption of the Bcr-Abl, Jak2 and HSP90 signaling network complex in leukemia cells. | 2015 Jan |
2 |
| 46 |
25870087 | Phase I/II Study of HSP90 Inhibitor AUY922 and Erlotinib for EGFR-Mutant Lung Cancer With Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors. | 2015 May 20 |
1 |
| 47 |
25955495 | Role of the novel HSP90 inhibitor AUY922 in hepatocellular carcinoma: Potential for therapy. | 2015 Aug |
1 |
| 48 |
26187127 | Co-targeting AR and HSP90 suppresses prostate cancer cell growth and prevents resistance mechanisms. | 2015 Oct |
1 |
| 49 |
26225840 | Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid liposarcoma. | 2015 Oct 28 |
2 |
| 50 |
26416354 | Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1. | 2015 Nov 3 |
1 |