| 1 |
35022315 | KDM6A Depletion in Breast Epithelial Cells Leads to Reduced Sensitivity to Anticancer Agents and Increased TGFβ Activity. | 2022 Apr 1 |
1 |
| 2 |
35136209 | The KDM6A-SPARCL1 axis blocks metastasis and regulates the tumour microenvironment of gastrointestinal stromal tumours by inhibiting the nuclear translocation of p65. | 2022 Jun |
1 |
| 3 |
33368310 | MiR-153-3p inhibits osteogenic differentiation of periodontal ligament stem cells through KDM6A-induced demethylation of H3K27me3. | 2021 Apr |
1 |
| 4 |
33633164 | A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition. | 2021 Feb 25 |
2 |
| 5 |
34465286 | Overexpression of UTX promotes tumor progression in Oral tongue squamous cell carcinoma patients receiving surgical resection: a case control study. | 2021 Sep 1 |
1 |
| 6 |
31201358 | Loss of KDM6A confers drug resistance in acute myeloid leukemia. | 2020 Jan |
2 |
| 7 |
31935506 | Identification of KMT2D and KDM6A variants by targeted sequencing from patients with Kabuki syndrome and other congenital disorders. | 2020 Mar 20 |
1 |
| 8 |
32071397 | Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization. | 2020 Apr |
1 |
| 9 |
32765772 | KDM6A suppresses hepatocellular carcinoma cell proliferation by negatively regulating the TGF-β/SMAD signaling pathway. | 2020 Sep |
2 |
| 10 |
32817139 | Lysine Demethylase KDM6A in Differentiation, Development, and Cancer. | 2020 Sep 28 |
4 |
| 11 |
32855205 | Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death. | 2020 Oct 15 |
2 |
| 12 |
32879445 | Histone 3 lysine-27 demethylase KDM6A coordinates with KMT2B to play an oncogenic role in NSCLC by regulating H3K4me3. | 2020 Oct |
1 |
| 13 |
32977832 | UTX/KDM6A suppresses AP-1 and a gliogenesis program during neural differentiation of human pluripotent stem cells. | 2020 Sep 25 |
3 |
| 14 |
33291558 | Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain. | 2020 Dec 4 |
1 |
| 15 |
30753822 | UTX Mutations in Human Cancer. | 2019 Feb 11 |
2 |
| 16 |
31587141 | Kabuki syndrome: review of the clinical features, diagnosis and epigenetic mechanisms. | 2019 Dec |
4 |
| 17 |
29220567 | Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. | 2018 Feb 6 |
1 |
| 18 |
29421189 | UTX - moonlighting in the cytoplasm? | 2018 Apr |
1 |
| 19 |
27983522 | Different expression patterns of histone H3K27 demethylases in renal cell carcinoma and bladder cancer. | 2017 |
1 |
| 20 |
28284523 | Demethylase Kdm6a epigenetically promotes IL-6 and IFN-β production in macrophages. | 2017 Jun |
1 |
| 21 |
28698146 | Epigenetic regulation of epithelial-mesenchymal transition by KDM6A histone demethylase in lung cancer cells. | 2017 Sep 2 |
1 |
| 22 |
28968467 | KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21CIP1 suppression of replication stress. | 2017 Oct |
1 |
| 23 |
26640146 | ASXL2 promotes proliferation of breast cancer cells by linking ERα to histone methylation. | 2016 Jul 14 |
1 |
| 24 |
26819089 | Epigenetic regulation of E-cadherin expression by the histone demethylase UTX in colon cancer cells. | 2016 Mar |
1 |
| 25 |
27039394 | Epigenetic Dysfunction in Turner Syndrome Immune Cells. | 2016 May |
1 |
| 26 |
27106782 | Prognostic value of UTX expression in patients with clear cell renal cell carcinoma. | 2016 Aug |
1 |
| 27 |
27638352 | MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer. | 2016 Nov 1 |
1 |
| 28 |
26280580 | RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome. | 2015 Sep |
1 |
| 29 |
26431949 | T Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX. | 2015 Oct 20 |
1 |
| 30 |
24123378 | EZH2 and KDM6A act as an epigenetic switch to regulate mesenchymal stem cell lineage specification. | 2014 Mar |
2 |
| 31 |
24491801 | UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells. | 2014 Mar 15 |
2 |
| 32 |
24561908 | The H3K27me3 demethylase UTX in normal development and disease. | 2014 May |
1 |
| 33 |
24798337 | Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase. | 2014 Jun 27 |
2 |
| 34 |
25071154 | Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia. | 2014 Oct 1 |
4 |
| 35 |
25132549 | Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia. | 2014 Oct 23 |
1 |
| 36 |
25225064 | Concurrent alterations in TERT, KDM6A, and the BRCA pathway in bladder cancer. | 2014 Sep 15 |
1 |
| 37 |
22986503 | A new horizon for epigenetic medicine? | 2013 Mar |
2 |
| 38 |
22801502 | The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming. | 2012 Aug 16 |
1 |
| 39 |
23155442 | Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid. | 2012 |
2 |
| 40 |
21245294 | Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming. | 2011 Feb 1 |
1 |
| 41 |
21248752 | Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. | 2011 Jan 27 |
1 |
| 42 |
22002947 | Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A. | 2011 Nov 1 |
2 |
| 43 |
20650264 | The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase. | 2010 Aug 20 |
1 |
| 44 |
21209387 | Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation. | 2010 |
1 |
| 45 |
19330029 | Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. | 2009 May |
1 |
| 46 |
17713478 | UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. | 2007 Oct 11 |
1 |