Carboxylic Acids

carboxylesterase 1 ; Homo sapiens







10 Article(s)
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1 34904522 Optimal pH 8.5 to 9 for the hydrolysis of vixotrigine and other basic substrates of carboxylesterase-1 in human liver microsomes. 2022 Feb 1
2 28126414 Recent progress in the discovery of natural inhibitors against human carboxylesterases. 2017 Mar 1
3 28775293 Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients. 2017 Aug 3 2
4 27196064 The Metabolism of Clopidogrel: CYP2C19 Is a Minor Pathway. 2016 Dec 1
5 25704243 Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans. 2015 Jun 2
6 24512105 Association between copy number variation losses and alcohol dependence across African American and European American ethnic groups. 2014 May 1
7 23111421 The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response. 2013 Jan 2
8 23386702 Reversible inhibition of human carboxylesterases by acyl glucuronides. 2013 Apr 3
9 19062296 Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis. 2009 Jan 1 1
10 17936933 Human carboxylesterases and their role in xenobiotic and endobiotic metabolism. 2007 1