Cocaine

carboxylesterase 1 ; Homo sapiens







14 Article(s)
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1 31717501 Catalytic Hydrolysis Mechanism of Cocaine by Human Carboxylesterase 1: An Orthoester Intermediate Slows Down the Reaction. 2019 Nov 9 3
2 29951737 The Development of Bacterial Carboxylesterase Biological Recognition Elements for Cocaine Detection. 2018 Aug 2
3 30095924 Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway. 2018 Sep 4 7
4 25445008 Contribution of human esterases to the metabolism of selected drugs of abuse. 2015 Jan 5 1
5 23647544 Investigation binding patterns of human carboxylesterase I (hCES I) with broad substrates by MD simulations. 2013 1
6 20649590 Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin. 2010 Aug 3
7 18273909 Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase. 2008 Feb 2
8 12679808 Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme. 2003 May 3
9 12773168 Human carboxylesterase 1: from drug metabolism to drug discovery. 2003 Jun 3
10 10381793 Binding and hydrolysis of meperidine by human liver carboxylesterase hCE-1. 1999 Jul 2
11 9169443 Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin. 1997 Jun 6 1
12 9311626 Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs. 1997 Sep 5
13 8930175 Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases. 1996 Nov 4
14 7980644 Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and cocaine. 1994 Nov 1 1