Serine

elastase, neutrophil expressed ; Homo sapiens







39 Article(s)
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Title
Pub. Year
#Total Relationships
1 34883205 Production and characterization of mono-PEGylated alpha-1 antitrypsin for augmentation therapy. 2022 Jan 25 1
2 35014748 Sequence preference and scaffolding requirement for the inhibition of human neutrophil elastase by ecotin peptide. 2022 Apr 2
3 35436320 Occurrence of a novel cleavage site for cathepsin G adjacent to the polybasic sequence within the proteolytically sensitive activation loop of the SARS-CoV-2 Omicron variant: The amino acid substitution N679K and P681H of the spike protein. 2022 1
4 35508753 High-level production of wild-type and oxidation-resistant recombinant alpha-1-antitrypsin in glycoengineered CHO cells. 2022 May 4 1
5 35631327 Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases. 2022 Apr 20 1
6 33239231 Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. 2021 Jan 1
7 33321445 Bioengineering of an elastase inhibitor from Caesalpinia echinata (Brazil wood) seeds. 2021 Feb 1
8 33494436 Protease-Specific Biomarkers to Analyse Protease Inhibitors for Emphysema Associated with Alpha 1-Antitrypsin Deficiency. An Overview of Current Approaches. 2021 Jan 21 1
9 33562184 Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage. 2021 Feb 7 1
10 33748632 Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein. 2021 Mar 16 1
11 34017121 Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. 2021 Jun 1
12 34056422 Sulfonated Nonsaccharide Heparin Mimetics Are Potent and Noncompetitive Inhibitors of Human Neutrophil Elastase. 2021 May 18 1
13 34072295 Trypsin-Like Proteases and Their Role in Muco-Obstructive Lung Diseases. 2021 May 29 1
14 34220840 Mapping Salivary Proteases in Sjögren's Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26. 2021 2
15 34292081 Proteinase 3 contributes to endothelial dysfunction in an experimental model of sepsis. 2021 Nov 1
16 34500777 Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase. 2021 Sep 2 2
17 34563669 1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors. 2021 Nov 15 1
18 34677831 d-Galactose treatment increases ACE2, TMPRSS2, and FURIN and reduces SERPINA1 mRNA expression in A549 human lung epithelial cells. 2021 Oct 22 1
19 34681796 Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases. 2021 Oct 15 1
20 34820446 The emerging role of proteases in α1-antitrypsin deficiency and beyond. 2021 Oct 1
21 32547155 Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies. 2020 1
22 32573571 Paper-based human neutrophil elastase detection device for clinical wound monitoring. 2020 Aug 7 2
23 32581778 The Natural Polypeptides as Significant Elastase Inhibitors. 2020 1
24 32588320 Neutrophil Elastase and Neutrophil Extracellular Traps in the Tumor Microenvironment. 2020 2
25 32657577 Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site. 2020 Aug 4 2
26 32759494 Gene therapy for alpha 1-antitrypsin deficiency with an oxidant-resistant human alpha 1-antitrypsin. 2020 Aug 6 1
27 33032202 Physics-driven identification of clinically approved and investigation drugs against human neutrophil serine protease 4 (NSP4): A virtual drug repurposing study. 2020 Dec 1
28 30626182 Activity-Based Near-Infrared Fluorogenic Probe for Enabling in Vitro and in Vivo Profiling of Neutrophil Elastase. 2019 Mar 19 1
29 31362723 Neutrophil elastase as a biomarker for bacterial infection in COPD. 2019 Jul 30 2
30 11312926 Development of orally active nonpeptidic inhibitors of human neutrophil elastase. 2001 Apr 12 1
31 10581030 Mutations in ELA2, encoding neutrophil elastase, define a 21-day biological clock in cyclic haematopoiesis. 1999 Dec 3
32 9822552 Design and synthesis of hydrazinopeptides and their evaluation as human leukocyte elastase inhibitors. 1998 Nov 19 1
33 7562931 Peptidyl alpha-ketoheterocyclic inhibitors of human neutrophil elastase. 3. In vitro and in vivo potency of a series of peptidyl alpha-ketobenzoxazoles. 1995 Sep 29 1
34 8073817 Evaluation of serine alpha 1-antitrypsin and polymorphonuclear leukocyte elastase contents and their immunogenetic correlation in psoriasis. 1994 1
35 2404977 Characterization of two azurphil granule proteases with active-site homology to neutrophil elastase. 1990 Feb 5 1
36 2966812 Fibronectin degradation products containing the cytoadhesive tetrapeptide stimulate human neutrophil degranulation. 1988 May 1
37 3257733 Inhibition of human neutrophil elastase by polyguanylic acid and other synthetic RNA homopolymers. 1988 1
38 3427074 Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA. 1987 Nov 17 1
39 3649251 Mechanism of slow-binding inhibition of human leukocyte elastase by trifluoromethyl ketones. 1987 May 19 1