halofuginone

glutamyl-prolyl-tRNA synthetase 1 ; Homo sapiens







10 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35466425 Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response. 2022 Jun 1 3
2 35636724 Prospects of halofuginone as an antiprotozoal drug scaffold. 2022 May 27 1
3 33791697 The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. 2021 Mar 26 3
4 32253314 Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. 2020 Apr 21 3
5 30773881 The Adaptive Proline Response in P. falciparum Is Independent of PfeIK1 and eIF2α Signaling. 2019 Apr 12 2
6 31046771 Amino acid response by Halofuginone in Cancer cells triggers autophagy through proteasome degradation of mTOR. 2019 May 2 2
7 28487390 Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress. 2017 May 9 2
8 28501621 Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with l-proline. 2017 Jun 24 5
9 25817387 Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis. 2015 May 5 1
10 24100331 Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone. 2013 Oct 3