| 1 |
35302851 | ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers. | 2022 Mar 18 |
1 |
| 2 |
33537800 | Diagnostic value of microRNA‑125b in peripheral blood mononuclear cells for pulmonary tuberculosis. | 2021 Apr |
1 |
| 3 |
33597213 | HIV-1 Nef-Induced Secretion of the Proinflammatory Protease TACE into Extracellular Vesicles Is Mediated by Raf-1 and Can Be Suppressed by Clinical Protein Kinase Inhibitors. | 2021 Apr 12 |
1 |
| 4 |
34298678 | Oncogenic Kinase Cascades Induce Molecular Mechanisms That Protect Leukemic Cell Models from Lethal Effects of De Novo dNTP Synthesis Inhibition. | 2021 Jul 10 |
2 |
| 5 |
34681164 | In Silico Prediction of the Phosphorylation of NS3 as an Essential Mechanism for Dengue Virus Replication and the Antiviral Activity of Quercetin. | 2021 Oct 19 |
1 |
| 6 |
34837907 | A Clinical Evaluation of Circulating MiR-106a and Raf-1 as Breast Cancer Diagnostic and Prognostic Markers. | 2021 Nov 1 |
1 |
| 7 |
31030682 | A severe clinical phenotype of Noonan syndrome with neonatal hypertrophic cardiomyopathy in the second case worldwide with RAF1 S259Y neomutation. | 2019 Apr 29 |
1 |
| 8 |
31352445 | Fibroblast Growth Factors: A Controlling Mechanism of Skin Aging. | 2019 |
1 |
| 9 |
29545175 | RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis. | 2018 Apr 15 |
3 |
| 10 |
30030377 | The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho-Ser-621 in the C terminus of CRAF. | 2018 Sep 14 |
2 |
| 11 |
28694330 | Phosphorylation of the C-Raf N Region Promotes Raf Dimerization. | 2017 Oct 1 |
1 |
| 12 |
27169363 | A Phos-tag SDS-PAGE method that effectively uses phosphoproteomic data for profiling the phosphorylation dynamics of MEK1. | 2016 Jul |
3 |
| 13 |
25713071 | Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway. | 2015 Apr 10 |
1 |
| 14 |
26058013 | Activation of RAF1 (c-RAF) by the Marine Alkaloid Lasonolide A Induces Rapid Premature Chromosome Condensation. | 2015 Jun 5 |
1 |
| 15 |
26295714 | Biophysical Characterization of Essential Phosphorylation at the Flexible C-Terminal Region of C-Raf with 14-3-3ζ Protein. | 2015 |
1 |
| 16 |
26333361 | Kinase-independent role for CRAF-driving tumour radioresistance via CHK2. | 2015 Sep 3 |
1 |
| 17 |
24330068 | Nuclear Raf-1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid-induced leukemic cell differentiation. | 2014 Feb |
1 |
| 18 |
24626525 | Cholera toxin, a typical protein kinase A activator, induces G1 phase growth arrest in human bladder transitional cell carcinoma cells via inhibiting the c-Raf/MEK/ERK signaling pathway. | 2014 May |
2 |
| 19 |
24746704 | Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors. | 2014 May 12 |
1 |
| 20 |
24929361 | Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling. | 2014 Jul |
3 |
| 21 |
25096573 | Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth. | 2014 Sep 26 |
1 |
| 22 |
23529931 | Endothelial RAF1/ERK activation regulates arterial morphogenesis. | 2013 May 9 |
1 |
| 23 |
23653349 | p21-activated kinase 1 (PAK1) can promote ERK activation in a kinase-independent manner. | 2013 Jul 5 |
1 |
| 24 |
23893412 | Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation. | 2013 Sep 20 |
4 |
| 25 |
24023871 | The HDAC inhibitor LBH589 induces ERK-dependent prometaphase arrest in prostate cancer via HDAC6 inactivation and down-regulation. | 2013 |
1 |
| 26 |
22592532 | Calcium/calmodulin-dependent protein kinase II (CaMKII) phosphorylates Raf-1 at serine 338 and mediates Ras-stimulated Raf-1 activation. | 2012 Jun 1 |
1 |
| 27 |
20688159 | Akt isoform-specific inhibition of MDA-MB-231 cell proliferation. | 2011 Jan |
1 |
| 28 |
20934465 | Akt-mediated signaling is induced by cytokines and cyclic adenosine monophosphate and suppresses hepatocyte inducible nitric oxide synthase expression independent of MAPK P44/42. | 2011 Jan |
1 |
| 29 |
21689459 | Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival. | 2011 Jun 21 |
1 |
| 30 |
21734462 | c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition. | 2011 Sep 15 |
2 |
| 31 |
22096607 | p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112. | 2011 |
1 |
| 32 |
20015475 | Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK. | 2010 Feb |
1 |
| 33 |
20052757 | Molecular and clinical analysis of RAF1 in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation. | 2010 Mar |
2 |
| 34 |
20056832 | Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathways. | 2010 Feb |
2 |
| 35 |
20212043 | Mammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 phosphorylation. | 2010 May 14 |
2 |
| 36 |
20371703 | A novel bile acid-activated vitamin D receptor signaling in human hepatocytes. | 2010 Jun |
1 |
| 37 |
20679480 | Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling. | 2010 Oct |
1 |
| 38 |
19185594 | The flaviviral methyltransferase is a substrate of Casein Kinase 1. | 2009 Apr |
2 |
| 39 |
19288477 | Ultrasound stimulates NF-kappaB activation and iNOS expression via the Ras/Raf/MEK/ERK signaling pathway in cultured preosteoblasts. | 2009 Jul |
1 |
| 40 |
19298812 | Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells. | 2009 Aug 1 |
3 |
| 41 |
19710016 | Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization. | 2009 Oct 23 |
2 |
| 42 |
18256541 | Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells. | 2008 Mar 1 |
1 |
| 43 |
18402774 | C-RAF activation promotes BAD poly-ubiquitylation and turn-over by the proteasome. | 2008 Jun 13 |
2 |
| 44 |
18465753 | p21 activated kinase 5 activates Raf-1 and targets it to mitochondria. | 2008 Sep 1 |
1 |
| 45 |
18757072 | Phosphorylation of yellow fever virus NS5 alters methyltransferase activity. | 2008 Oct 25 |
2 |
| 46 |
17055484 | c-jun amino-terminal kinase and mitogen activated protein kinase 1/2 mediate hepatocyte growth factor-induced migration of brain endothelial cells. | 2007 Jan 1 |
1 |
| 47 |
17277048 | Raf-1 kinase mediates adenylyl cyclase sensitization by TNF-alpha in human airway smooth muscle cells. | 2007 Jun |
1 |
| 48 |
17462920 | C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB. | 2007 May |
1 |
| 49 |
17613527 | Unique N-region determines low basal activity and limited inducibility of A-RAF kinase: the role of N-region in the evolutionary divergence of RAF kinase function in vertebrates. | 2007 Sep 7 |
3 |
| 50 |
17785857 | Zinc-dependent suppression of TNF-alpha production is mediated by protein kinase A-induced inhibition of Raf-1, I kappa B kinase beta, and NF-kappa B. | 2007 Sep 15 |
3 |