Paclitaxel

Raf-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







18 Article(s)
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1 31334335 FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter. 2019 Sep 27 1
2 24729449 Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer. 2014 Jun 1
3 16101130 Biomarkers of anticancer activity of R115777 (Tipifarnib, Zarnestra) in human breast cancer models in vitro. 2005 Sep-Oct 1
4 14742319 Id-1-induced Raf/MEK pathway activation is essential for its protective role against taxol-induced apoptosis in nasopharyngeal carcinoma cells. 2004 Jun 1
5 15159015 Insulin can modulate MCF-7 cell response to paclitaxel. 2004 Jun 25 1
6 12510025 Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells. 2003 Apr 1
7 12631622 Raf-1 and Bcl-2 induce distinct and common pathways that contribute to breast cancer drug resistance. 2003 Mar 1
8 12691824 Down-regulation of Raf-1 kinase is associated with paclitaxel resistance in human breast cancer MCF-7/Adr cells. 2003 Apr 10 4
9 12087097 Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel. 2002 Sep 6 9
10 10854551 Raf-1 kinase activity predicts for paclitaxel resistance in TP53mut, but not TP53wt human ovarian cancer cells. 2000 Jul-Aug 10
11 11001384 Differential impact of Raf-1 kinase activity on tumor cell resistance to paclitaxel and docetaxel. 2000 Jul 2
12 11042690 A novel assay for the measurement of Raf-1 kinase activity. 2000 Oct 12 1
13 10400418 Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells. 1999 Jul 2
14 9607567 High Raf-1 kinase activity protects human tumor cells against paclitaxel-induced cytotoxicity. 1998 May 10
15 9721870 Mechanisms of Taxol-induced cell death are concentration dependent. 1998 Aug 15 2
16 9925253 Paclitaxel is preferentially cytotoxic to human cervical tumor cells with low Raf-1 kinase activity: implications for paclitaxel-based chemoradiation regimens. 1998 Sep 5
17 8988053 Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death. 1997 Jan 1 6
18 9067280 Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human acute myeloid leukemia HL-60 cells. 1997 Mar 15 2