| 1 |
29963858 | Self-Assembled Double-Bundle DNA Tetrahedron for Efficient Antisense Delivery. | 2018 Jul 18 |
1 |
| 2 |
19704336 | Phase I study of the c-raf-1 antisense oligonucleotide ISIS 5132 in combination with carboplatin and paclitaxel in patients with previously untreated, advanced non-small cell lung cancer. | 2009 Sep |
1 |
| 3 |
16184551 | Comparison of strategies targeting Raf-1 mRNA in ovarian cancer. | 2006 Mar 15 |
1 |
| 4 |
16465392 | Gene expression profile by inhibiting Raf-1 protein kinase in breast cancer cells. | 2006 Mar |
2 |
| 5 |
15041731 | Antisense oligonucleotide targeting of Raf-1: importance of raf-1 mRNA expression levels and raf-1-dependent signaling in determining growth response in ovarian cancer. | 2004 Mar 15 |
2 |
| 6 |
15067340 | Enhanced therapeutic effects of doxorubicin and paclitaxel in combination with liposome-entrapped ends-modified raf antisense oligonucleotide against human prostate, lung and breast tumor models. | 2004 May |
1 |
| 7 |
15547762 | The role of Raf-1 in radiation resistance of human hepatocellular carcinoma Hep G2 cells. | 2004 Dec |
1 |
| 8 |
12584738 | C-Raf controlled pathways in the protection of tumor cells from apoptosis. | 2003 Apr 20 |
1 |
| 9 |
12694666 | Phase II study of CGP 69846A (ISIS 5132) in recurrent epithelial ovarian cancer: an NCIC clinical trials group study (NCIC IND.116). | 2003 Apr |
1 |
| 10 |
12917261 | Protein kinase Cbeta1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion. | 2003 Sep |
1 |
| 11 |
12947394 | RAF antisense oligonucleotide as a tumor radiosensitizer. | 2003 Sep 1 |
1 |
| 12 |
14654778 | Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells. | 2003 Dec 4 |
2 |
| 13 |
12022686 | In vivo pro-apoptotic and antitumor efficacy of a c-Raf antisense phosphorothioate oligonucleotide: relationship to tumor size. | 2002 Feb |
2 |
| 14 |
12149272 | Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes. | 2002 Oct 11 |
2 |
| 15 |
12359742 | Inhibition of hepatic endothelial E-selectin expression by C-raf antisense oligonucleotides blocks colorectal carcinoma liver metastasis. | 2002 Oct 1 |
1 |
| 16 |
11335788 | Increased sensitivity to cytosine arabinoside in human leukemia by c-raf-1 antisense oligonucleotides. | 2001 Apr |
1 |
| 17 |
11459784 | Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway. | 2001 Aug |
2 |
| 18 |
11742498 | Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancer. | 2001 Nov 30 |
1 |
| 19 |
10815879 | A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer. | 2000 May |
1 |
| 20 |
11198925 | In vivo expression of single-stranded DNA in mammalian cells with DNA enzyme sequences targeted to C-raf. | 2000 Dec |
1 |
| 21 |
21390806 | Inhibition of Cell Growth by Antisense Oligonucleotides Targeting the Growth-Related Protein Kinase c-raf. | 2000 |
1 |
| 22 |
10220029 | Synthesis of an antisense oligonucleotide targeted against C-raf kinase: efficient oligonucleotide synthesis without chlorinated solvents. | 1999 Mar |
2 |
| 23 |
10561280 | Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A). | 1999 Jul |
1 |
| 24 |
9837893 | A role for c-Raf kinase and Ha-Ras in cytokine-mediated induction of cell adhesion molecules. | 1998 Dec 11 |
2 |
| 25 |
9007224 | Raf-1 protein is required for growth factor-induced proliferation of primitive hematopoietic progenitors stimulated with synergistic combinations of cytokines. | 1997 |
2 |
| 26 |
9383572 | First- and second-generation antisense oligonucleotide inhibitors targeted against human c-raf kinase. | 1997 |
2 |
| 27 |
9450911 | Molecular and cellular characterization of baboon C-Raf as a target for antiproliferative effects of antisense oligonucleotides. | 1997 Dec |
2 |
| 28 |
9815797 | Antitumor activity of a C-raf antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted subcutaneously into nude mice. | 1997 Jul |
1 |
| 29 |
8585963 | The effect of c-raf antisense oligonucleotides on growth factor-induced proliferation of hematopoietic cells. | 1996 |
2 |
| 30 |
8978841 | 2'-O-aminopropyl ribonucleotides: a zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides. | 1996 Dec 20 |
1 |
| 31 |
7539043 | Raf-1 protein is required for growth factor-induced proliferation of hematopoietic cells. | 1995 Jun 1 |
1 |