Adenosine Triphosphate

Raf-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







12 Article(s)
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Pub. Year
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1 32269299 RAF kinase dimerization: implications for drug discovery and clinical outcomes. 2020 May 1
2 26810260 Discovery of highly selective CRAF inhibitors, 3-carboxamido-2H-indazole-6-arylamide: In silico FBLD design, synthesis and evaluation. 2016 Feb 15 1
3 27633746 Enrichment of Metabolite-Binding Proteins by Affinity Elution in Tandem Hydrophobic Interaction Chromatography (AETHIC) Reveals RKIP Regulating ERK Signaling in an ATP-Dependent Manner. 2016 Oct 7 5
4 25611072 Structural investigation of B-Raf paradox breaker and inducer inhibitors. 2015 Feb 26 1
5 26344764 Drug Resistance Resulting from Kinase Dimerization Is Rationalized by Thermodynamic Factors Describing Allosteric Inhibitor Effects. 2015 Sep 22 1
6 21441104 Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF. 2011 Apr 12 1
7 19595761 The C-terminus of Raf-1 acts as a 14-3-3-dependent activation switch. 2009 Nov 2
8 14706820 Engineering the serine/threonine protein kinase Raf-1 to utilise an orthogonal analogue of ATP substituted at the N6 position. 2004 Jan 2 3
9 15556759 3D-QSAR CoMFA, CoMSIA studies on substituted ureas as Raf-1 kinase inhibitors and its confirmation with structure-based studies. 2004 Dec 15 1
10 12244094 Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1. 2002 Nov 22 1
11 9657959 Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein. 1998 Jul 5 1
12 9285556 Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1. 1997 Aug 28 1