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Raf-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







11 Article(s)
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1 12694666 Phase II study of CGP 69846A (ISIS 5132) in recurrent epithelial ovarian cancer: an NCIC clinical trials group study (NCIC IND.116). 2003 Apr 1
2 12917261 Protein kinase Cbeta1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion. 2003 Sep 1
3 15000822 The reduction of Raf-1 protein by phosphorothioate ODNs and siRNAs targeted to the same two mRNA sequences. 2003 1
4 12022686 In vivo pro-apoptotic and antitumor efficacy of a c-Raf antisense phosphorothioate oligonucleotide: relationship to tumor size. 2002 Feb 2
5 10815879 A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer. 2000 May 1
6 11249625 Development of antisense oligodeoxynucleotides for transplantation. 2000 Jun 1
7 10097067 A cytosine analog that confers enhanced potency to antisense oligonucleotides. 1999 Mar 30 1
8 9072302 Inhibition of Raf-1 protein kinase by antisense phosphorothioate oligodeoxyribonucleotide is associated with sensitization of human laryngeal squamous carcinoma cells to gamma radiation. 1997 Jan-Feb 1
9 8640558 Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. 1996 Jun 4
10 8978841 2'-O-aminopropyl ribonucleotides: a zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides. 1996 Dec 20 1
11 8986837 Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo. 1996 Dec 24 1