geldanamycin

Raf-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







20 Article(s)
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Title
Pub. Year
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1 19167484 Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity. 2009 May 1
2 18559533 Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma. 2008 Jun 15 1
3 16827123 Inhibition of neuroblastoma xenograft growth by Hsp90 inhibitors. 2006 May-Jun 2
4 15846067 Kinase-addiction and bi-phasic sensitivity-resistance of Bcr-Abl- and Raf-1-expressing cells to imatinib and geldanamycin. 2005 Apr 3
5 12471618 Geldanamycin decreases Raf-1 and Akt levels and induces apoptosis in neuroblastomas. 2003 Jan 20 5
6 12680188 Src tyrosine kinase but not activated Ras augments sensitivity to taxanes through apoptosis in human adenocarcinoma cells. 2003 Jan-Feb 1
7 14633716 Free and N-(2-hydroxypropyl)methacrylamide copolymer-bound geldanamycin derivative induce different stress responses in A2780 human ovarian carcinoma cells. 2003 Nov 15 1
8 11823472 Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes. 2002 Apr 5 1
9 11960322 Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs. 2002 Apr 2
10 11280726 Geldanamycin and its analogue 17-allylamino-17-demethoxygeldanamycin lowers Bcr-Abl levels and induces apoptosis and differentiation of Bcr-Abl-positive human leukemic blasts. 2001 Mar 1 1
11 10701840 The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation. 2000 Jan 1
12 10927059 Depletion of Raf-1 protooncogene by geldanamycin causes apoptosis in human luteinized granulosa cells. 2000 Aug 3
13 10024519 Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cells. 1999 Mar 1 1
14 10228164 Non-transcriptional action of oestradiol and progestin triggers DNA synthesis. 1999 May 4 2
15 10454292 Cyclic stretch up-regulates proliferation and heat shock protein 90 expression in human melanocytes. 1999 Aug 1
16 9622079 Metabolism of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) by murine and human hepatic preparations. 1998 Jun 1 1
17 9699663 Bcl-xL is phosphorylated in malignant cells following microtubule disruption. 1998 Aug 1 1
18 9067280 Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human acute myeloid leukemia HL-60 cells. 1997 Mar 15 1
19 9137531 Depletion of p185erbB2, Raf-1 and mutant p53 proteins by geldanamycin derivatives correlates with antiproliferative activity. 1997 4
20 9367823 Geldanamycin-induced destabilization of Raf-1 involves the proteasome. 1997 Oct 29 5