| 1 |
33242144 | Protective Effects of ShcA Protein Silencing for Photothrombotic Cerebral Infarction. | 2021 Oct |
1 |
| 2 |
34821107 | [Effect of swimming training on the expression of PKC δ/p66Shc protein in mouse myocardium]. | 2021 Nov |
1 |
| 3 |
32659284 | LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis. | 2020 Sep 15 |
1 |
| 4 |
33159035 | circ-CBFB upregulates p66Shc to perturb mitochondrial dynamics in APAP-induced liver injury. | 2020 Nov 6 |
1 |
| 5 |
33302436 | Lack of Contribution of p66shc to Pressure Overload-Induced Right Heart Hypertrophy. | 2020 Dec 8 |
1 |
| 6 |
29077881 | Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity. | 2019 Jan 21 |
2 |
| 7 |
30867846 | p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species. | 2019 |
9 |
| 8 |
29624862 | The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E-transformed cells. | 2018 Jun |
2 |
| 9 |
29721150 | p66Shc Inactivation Modifies RNS Production, Regulates Sirt3 Activity, and Improves Mitochondrial Homeostasis, Delaying the Aging Process in Mouse Brain. | 2018 |
3 |
| 10 |
30047409 | Hyperglycaemia-induced epigenetic changes drive persistent cardiac dysfunction via the adaptor p66Shc. | 2018 Oct 1 |
1 |
| 11 |
30072100 | Isocitrate dehydrogenase 2 deficiency induces endothelial inflammation via p66sh-mediated mitochondrial oxidative stress. | 2018 Sep 10 |
2 |
| 12 |
27431297 | Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. | 2017 Apr |
4 |
| 13 |
27960536 | Oxidative Stress-Induced miR-200c Disrupts the Regulatory Loop Among SIRT1, FOXO1, and eNOS. | 2017 Aug 20 |
1 |
| 14 |
28137876 | Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction. | 2017 Feb 14 |
5 |
| 15 |
29041825 | Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation. | 2017 Dec |
2 |
| 16 |
27157635 | The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss. | 2016 May 9 |
4 |
| 17 |
25499814 | High-dose alcohol induces reactive oxygen species-mediated apoptosis via PKC-β/p66Shc in mouse primary cardiomyocytes. | 2015 Jan 9 |
1 |
| 18 |
25810038 | The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells. | 2015 Jun |
2 |
| 19 |
26122877 | p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans. | 2015 Oct |
1 |
| 20 |
24295239 | A critical role of Fas-associated protein with death domain phosphorylation in intracellular reactive oxygen species homeostasis and aging. | 2014 Jul 1 |
3 |
| 21 |
24845561 | P66Shc mediates increased platelet activation and aggregation in hypercholesterolemia. | 2014 Jul 11 |
1 |
| 22 |
25012499 | Enhanced age-dependent cerebrovascular dysfunction is mediated by adaptor protein p66Shc. | 2014 Aug 20 |
1 |
| 23 |
25147340 | Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species. | 2014 Oct |
1 |
| 24 |
25150941 | p66(Shc)-induced redox changes drive endothelial insulin resistance. | 2014 Oct |
6 |
| 25 |
25556747 | Role of p66Shc gene in human longevity. | 2014 Dec |
1 |
| 26 |
23008506 | Deletion of the ageing gene p66(Shc) reduces early stroke size following ischaemia/reperfusion brain injury. | 2013 Jan |
2 |
| 27 |
23092318 | The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis. | 2013 |
1 |
| 28 |
23524280 | The p66(Shc) gene paves the way for healthspan: evolutionary and mechanistic perspectives. | 2013 Jun |
4 |
| 29 |
22277070 | Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis. | 2012 Feb |
1 |
| 30 |
22642111 | [P66shc action on resistance of colon carcinoma RKO cells to oxidative stress]. | 2012 Jan-Feb |
4 |
| 31 |
22833725 | Genetic inactivation of mitochondria-targeted redox enzyme p66ShcA preserves neuronal viability and mitochondrial integrity in response to oxidative challenges. | 2012 |
1 |
| 32 |
21616139 | P66Shc mediated ferritin degradation--a novel mechanism of ROS formation. | 2011 Aug 1 |
3 |
| 33 |
22030390 | Glucocorticoids and tumor necrosis factor α increase oxidative stress and suppress Wnt protein signaling in osteoblasts. | 2011 Dec 30 |
4 |
| 34 |
19892704 | Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice. | 2010 Jan 8 |
2 |
| 35 |
19918794 | Intracellular redox imbalance and extracellular amino acid metabolic abnormality contribute to arsenic-induced developmental retardation in mouse preimplantation embryos. | 2010 Feb |
1 |
| 36 |
20053790 | p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury. | 2010 May |
3 |
| 37 |
20689155 | P66SHC and ageing: ROS and TOR? | 2010 Aug |
2 |
| 38 |
20739391 | p66Shc mediates high-glucose and angiotensin II-induced oxidative stress renal tubular injury via mitochondrial-dependent apoptotic pathway. | 2010 Nov |
1 |
| 39 |
19103250 | Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination. | 2009 Feb 5 |
2 |
| 40 |
19362067 | The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury. | 2009 Jul |
6 |
| 41 |
18490896 | Role of the life span determinant P66(shcA) in ethanol-induced liver damage. | 2008 Jul |
3 |
| 42 |
18504439 | Mitochondrial redox signaling by p66Shc is involved in regulating androgenic growth stimulation of human prostate cancer cells. | 2008 Aug 28 |
4 |
| 43 |
18511487 | Permanent embryo arrest: molecular and cellular concepts. | 2008 Aug |
1 |
| 44 |
18772327 | The role of p66Shc deletion in age-associated arterial dysfunction and disease states. | 2008 Nov |
1 |
| 45 |
18838380 | p66Shc-generated oxidative signal promotes fat accumulation. | 2008 Dec 5 |
7 |
| 46 |
17360381 | Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress. | 2007 Mar 20 |
4 |
| 47 |
17611735 | Ablation of the gene encoding p66Shc protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation. | 2007 Sep |
5 |
| 48 |
16481327 | The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism. | 2006 Apr 14 |
1 |
| 49 |
16519809 | Search for genetic variants in the p66Shc longevity gene by PCR-single strand conformational polymorphism in patients with early-onset cardiovascular disease. | 2006 Mar 6 |
2 |
| 50 |
16731826 | Deletion of p66Shc longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress. | 2006 Jun |
4 |