Dantrolene

ryanodine receptor 2, cardiac ; Mus musculus







8 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 32531044 Stretch-induced sarcoplasmic reticulum calcium leak is causatively associated with atrial fibrillation in pressure-overloaded hearts. 2021 Mar 21 1
2 33790404 Enhancing calmodulin binding to ryanodine receptor is crucial to limit neuronal cell loss in Alzheimer disease. 2021 Mar 31 1
3 34955889 The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool. 2021 1
4 31635807 Dantrolene prevents ventricular tachycardia by stabilizing the ryanodine receptor in pressure- overload induced failing hearts. 2020 Jan 1 4
5 29402414 CaMKII-mediated phosphorylation of RyR2 plays a crucial role in aberrant Ca2+ release as an arrhythmogenic substrate in cardiac troponin T-related familial hypertrophic cardiomyopathy. 2018 Feb 19 2
6 27318036 CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift. 2016 Sep 4
7 23284867 Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease. 2012 1
8 20944434 Dantrolene, a therapeutic agent for malignant hyperthermia, inhibits catecholaminergic polymorphic ventricular tachycardia in a RyR2(R2474S/+) knock-in mouse model. 2010 Nov 4