Tretinoin

aldehyde dehydrogenase 1 family member A2 ; Homo sapiens







82 Article(s)
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Pub. Year
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1 35213790 Evidence of depot-specific regulation of all-trans-retinoic acid biosynthesis in human adipose tissue. 2022 Jun 2
2 35574006 Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis. 2022 2
3 33378690 Peanut protein acts as a TH2 adjuvant by inducing RALDH2 in human antigen-presenting cells. 2021 Jul 1
4 33565183 Biallelic hypomorphic variants in ALDH1A2 cause a novel lethal human multiple congenital anomaly syndrome encompassing diaphragmatic, pulmonary, and cardiovascular defects. 2021 May 1
5 33648532 Aberrant regulation of retinoic acid signaling genes in cerebral arterio venous malformation nidus and neighboring astrocytes. 2021 Mar 1 1
6 34572134 The Presence and Potential Role of ALDH1A2 in the Glioblastoma Microenvironment. 2021 Sep 20 2
7 31165892 Independent Methylome-Wide Association Studies of Schizophrenia Detect Consistent Case-Control Differences. 2020 Feb 26 1
8 32209473 CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b-CD103+ DCs. 2020 Mar 24 4
9 32258025 Inhibition of GSK3 Represses the Expression of Retinoic Acid Synthetic Enzyme ALDH1A2 via Wnt/β-Catenin Signaling in WiT49 Cells. 2020 3
10 32961175 Retinoic acid synthesis by a population of choroidal stromal cells. 2020 Dec 1
11 30632787 Gen1 Modulates Metanephric Morphology Through Retinoic Acid Signaling. 2019 Mar 1
12 30661714 Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury. 2019 Mar 1
13 30885956 Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality. 2019 May 1 3
14 31615043 ALDH1A2 Is a Candidate Tumor Suppressor Gene in Ovarian Cancer. 2019 Oct 14 2
15 29076503 Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders. 2018 Jan 1
16 29240402 Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors. 2018 Mar 16 1
17 29321611 Acetaldehyde inhibits retinoic acid biosynthesis to mediate alcohol teratogenicity. 2018 Jan 10 4
18 29986869 RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation. 2018 Aug 2 1
19 30379862 Altered hepatic genes related to retinol metabolism and plasma retinol in patients with non-alcoholic fatty liver disease. 2018 2
20 30409702 Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. 2018 Dec 1 2
21 28361034 Combinatorial Ranking of Gene Sets to Predict Disease Relapse: The Retinoic Acid Pathway in Early Prostate Cancer. 2017 1
22 28423181 Mesenteric lymph node CD11b- CD103+ PD-L1High dendritic cells highly induce regulatory T cells. 2017 Sep 1
23 28677722 Regulation of retinoic acid synthetic enzymes by WT1 and HDAC inhibitors in 293 cells. 2017 Sep 2
24 26374207 Expression of the retinoic acid catabolic enzyme CYP26B1 in the human brain to maintain signaling homeostasis. 2016 Jul 1
25 27001866 Kinetic characterization and regulation of the human retinaldehyde dehydrogenase 2 enzyme during production of retinoic acid. 2016 May 15 5
26 27166374 Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling. 2016 Sep 19 1
27 27670072 Retinaldehyde dehydrogenase 2 as a molecular adjuvant for enhancement of mucosal immunity during DNA vaccination. 2016 Nov 4 4
28 27724856 Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma. 2016 Oct 10 1
29 25208926 Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumours. 2015 Jan 1
30 25427913 Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers. 2015 1
31 25502770 Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations. 2015 Feb 2
32 25793304 Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye. 2015 4
33 26023078 Deregulation of Retinaldehyde Dehydrogenase 2 Leads to Defective Angiogenic Function of Endothelial Colony-Forming Cells in Pediatric Moyamoya Disease. 2015 Jul 1
34 26101153 Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport. 2015 Jun 23 1
35 26634247 Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma. 2015 Dec 3 2
36 24524833 Levels of the retinoic acid synthesizing enzyme aldehyde dehydrogenase-1A2 are lower in testicular tissue from men with infertility. 2014 Apr 1
37 24594504 Aldehyde dehydrogenase 1A1: friend or foe to female metabolism? 2014 Mar 3 2
38 24788806 Retinoic acid and GM-CSF coordinately induce retinal dehydrogenase 2 (RALDH2) expression through cooperation between the RAR/RXR complex and Sp1 in dendritic cells. 2014 6
39 25149081 Astrocyte-derived retinoic acid: a novel regulator of blood-brain barrier function in multiple sclerosis. 2014 Nov 1
40 25240927 Generation of the epicardial lineage from human pluripotent stem cells. 2014 Oct 1
41 23833249 RDH10, RALDH2, and CRABP2 are required components of PPARγ-directed ATRA synthesis and signaling in human dendritic cells. 2013 Sep 2
42 23960232 IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2. 2013 Sep 15 1
43 23975865 Parasite infections in multiple sclerosis modulate immune responses through a retinoic acid-dependent pathway. 2013 Oct 1 1
44 24074870 Retinoic acid signaling is essential for embryonic hematopoietic stem cell development. 2013 Sep 26 2
45 24377748 Duplication of the ALDH1A2 gene in association with pentalogy of Cantrell: a case report. 2013 Dec 30 1
46 22689466 Patterning of retinoic acid signaling and cell proliferation in the hippocampus. 2012 Nov 4
47 21343363 Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2. 2011 Mar 3
48 21419270 Retinoic acid production by intestinal dendritic cells. 2011 1
49 21663736 WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways. 2011 Aug 15 1
50 20308937 Newborn serum retinoic acid level is associated with variants of genes in the retinol metabolism pathway. 2010 Jun 3