Guanosine Triphosphate

guanylate binding protein 1 ; Homo sapiens







28 Article(s)
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1 32352209 Catalytic activity of human guanylate-binding protein 1 coupled to the release of structural restraints imposed by the C-terminal domain. 2021 Jan 3
2 33113220 Stimulation of GMP formation in hGBP1 is mediated by W79 and its effect on the antiviral activity. 2021 May 2
3 33405388 Structural requirements for membrane binding of human guanylate-binding protein 1. 2021 Jul 1
4 32433976 hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis. 2020 May 19 3
5 30556562 Exposing catalytic versatility of GTPases: taking reaction detours in mutants of hGBP1 enzyme without additional energetic cost. 2019 Jan 2 1
6 28451182 The GTPase hGBP1 converts GTP to GMP in two steps via proton shuttle mechanisms. 2017 Jan 1 4
7 27071416 Tetrameric assembly of hGBP1 is crucial for both stimulated GMP formation and antiviral activity. 2016 Jun 15 2
8 25081641 GTP is an allosteric modulator of the interaction between the guanylate-binding protein 1 and the prosurvival kinase PIM1. 2015 Feb 16 3
9 26760981 Guanylate-binding protein 1 (GBP1) promotes lymph node metastasis in human esophageal squamous cell carcinoma. 2015 Dec 2
10 22059445 The guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysis. 2012 Jan 2
11 22458356 Immobilization of biotinylated hGBP1 in a defined orientation on surfaces is crucial for uniform interaction with analyte proteins and catalytic activity. 2012 Apr 17 2
12 22607347 Tetramerization of human guanylate-binding protein 1 is mediated by coiled-coil formation of the C-terminal α-helices. 2012 Jul 2
13 22859948 Insight into temperature dependence of GTPase activity in human guanylate binding protein-1. 2012 1
14 21142871 The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase. 2011 Jan 2
15 20923658 Dimerization and its role in GMP formation by human guanylate binding proteins. 2010 Oct 6 1
16 21219034 Human guanylate-binding protein 1 as a model system investigated by several surface techniques. 2010 Dec 1
17 19150356 Role of individual domains and identification of internal gap in human guanylate binding protein-1. 2009 Feb 27 1
18 19463820 Nucleotide dependent cysteine reactivity of hGBP1 uncovers a domain movement during GTP hydrolysis. 2009 Jun 18 5
19 16873363 Transient kinetic investigation of GTP hydrolysis catalyzed by interferon-gamma-induced hGBP1 (human guanylate binding protein 1). 2006 Sep 29 7
20 15937107 Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor. 2005 Jun 14 1
21 16413296 Nucleotide binding and self-stimulated GTPase activity of human guanylate-binding protein 1 (hGBP1). 2005 1
22 15504415 Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis. 2004 Nov 12 2
23 10676968 Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. 2000 Feb 3 2
24 10970849 Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. 2000 Sep 1 4
25 10493878 Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif. 1999 Sep 17 4
26 8706832 GTPase properties of the interferon-induced human guanylate-binding protein 2. 1996 Jul 15 1
27 8830800 Prenylation of an interferon-gamma-induced GTP-binding protein: the human guanylate binding protein, huGBP1. 1996 Sep 1
28 7512561 The interferon-induced 67-kDa guanylate-binding protein (hGBP1) is a GTPase that converts GTP to GMP. 1994 Apr 15 5