NAD

sirtuin 5 ; Homo sapiens







28 Article(s)
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Pub. Year
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1 34199982 The Mystery of Extramitochondrial Proteins Lysine Succinylation. 2021 Jun 4 1
2 34330933 Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells. 2021 Jul 30 2
3 34461505 Discovery of new human Sirtuin 5 inhibitors by mimicking glutaryl-lysine substrates. 2021 Dec 5 1
4 32846968 Subcellular Localization and Mitotic Interactome Analyses Identify SIRT4 as a Centrosomally Localized and Microtubule Associated Protein. 2020 Aug 24 1
5 32991157 Desuccinylation-Triggered Peptide Self-Assembly: Live Cell Imaging of SIRT5 Activity and Mitochondrial Activity Modulation. 2020 Oct 21 1
6 33046741 An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells. 2020 Oct 12 2
7 33103371 Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1. 2020 Dec 2
8 33230181 SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease. 2020 Nov 23 1
9 31333804 SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis. 2019 1
10 31456942 SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway. 2019 2
11 31843902 SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis. 2019 Dec 16 1
12 28707979 Emerging Roles for SIRT5 in Metabolism and Cancer. 2018 Mar 10 1
13 29115436 SIRT5 promotes cell proliferation and invasion in hepatocellular carcinoma by targeting E2F1. 2018 Jan 2
14 29514063 The Mitochondrial Acylome Emerges: Proteomics, Regulation by Sirtuins, and Metabolic and Disease Implications. 2018 Mar 6 1
15 27577743 Sirtuin 5 is Anti-apoptotic and Anti-oxidative in Cultured SH-EP Neuroblastoma Cells. 2017 Jan 4
16 28461090 NAD+ dependent deacetylase Sirtuin 5 rescues the innate inflammatory response of endotoxin tolerant macrophages by promoting acetylation of p65. 2017 Jul 1
17 28631845 Mild metabolic perturbations alter succinylation of mitochondrial proteins. 2017 Nov 1
18 26574954 Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins. 2016 Jan 1
19 24848608 A succinyl lysine-based photo-cross-linking peptide probe for Sirtuin 5. 2014 Jul 7 1
20 25070488 SIRT5 facilitates cancer cell growth and drug resistance in non-small cell lung cancer. 2014 Nov 2
21 22583019 Substrates for efficient fluorometric screening employing the NAD-dependent sirtuin 5 lysine deacylase (KDAC) enzyme. 2012 Jun 14 1
22 22767592 The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5). 2012 Aug 17 5
23 22849721 Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5. 2012 Sep 7 1
24 23028781 Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition. 2012 2
25 24900427 Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5. 2012 Dec 13 1
26 22076378 Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. 2011 Nov 11 1
27 17355872 Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin. 2007 Mar 1
28 16484774 Assignment of the NAD-dependent deacetylase sirtuin 5 gene (SIRT5) to human chromosome band 6p23 by in situ hybridization. 2006 6