Dihydrotestosterone

steroid 5 alpha-reductase 2 ; Homo sapiens







77 Article(s)
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Pub. Year
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1 35613877 Possible testosterone redundancy for 5α-dihydrotestosterone in the masculinization of mouse external genitalia. 2022 May 24 1
2 33833737 Profiles of 5α-Reduced Androgens in Humans and Eels: 5α-Dihydrotestosterone and 11-Ketodihydrotestosterone Are Active Androgens Produced in Eel Gonads. 2021 4
3 32702725 Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride. 2020 Jul 15 2
4 32732174 Molecular genetic analysis of AKR1C2-4 and HSD17B6 genes in subjects 46,XY with hypospadias. 2020 Oct 1
5 33110062 Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride. 2020 Oct 27 2
6 31272082 Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study. 2019 Aug 1 1
7 31601057 In silico screening of potential lead compounds against 3-oxo-5-alpha-steroid 4-dehydrogenase 2 for treating prostate cancer. 2019 Oct 5 1
8 32894851 Spectrum of Pathogenic Variants in SRD5A2 in Indian Children with 46,XY Disorders of Sex Development and Clinically Suspected Steroid 5α-Reductase 2 Deficiency. 2019 3
9 29610568 Longer TA repeat but not V89L polymorphisms in the SRD5A2 gene may confer acne risk in the Chinese population. 2018 Feb 1
10 27848231 Association of SRD5A2 gene mutations with risk of hypospadias in the Iranian population. 2017 Apr 4
11 28323036 Targeting androgen receptor versus targeting androgens to suppress castration resistant prostate cancer. 2017 Jul 1 1
12 28324044 Inverse Regulation of DHT Synthesis Enzymes 5α-Reductase Types 1 and 2 by the Androgen Receptor in Prostate Cancer. 2017 Apr 1 1
13 26574953 Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man. 2016 Jan 1
14 26789780 Epidemiological and Mendelian Randomization Studies of Dihydrotestosterone and Estradiol and Leukocyte Telomere Length in Men. 2016 Mar 2
15 27386051 Finasteride in Hidradenitis Suppurativa: A "Male" Therapy for a Predominantly "Female" Disease. 2016 Jun 1
16 25598933 The association of 5-alpha reductase type 2 (SRD5A2) gene polymorphisms with prostate cancer in a Korean population. 2015 Jan 5
17 25735326 SRD5A2 gene polymorphisms and the risk of benign prostatic hyperplasia but not prostate cancer. 2015 2
18 25974403 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes. 2015 Aug 1
19 24277450 Importance of 5α-reductase gene polymorphisms on circulating and intraprostatic androgens in prostate cancer. 2014 Feb 1 1
20 24326421 Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial. 2014 Feb 15 1
21 24793988 Steroidogenesis of the testis -- new genes and pathways. 2014 May 4
22 24898559 Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride. 2014 Nov 1
23 23505265 Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms. 2013 Apr 4
24 24012728 Novel nucleotide insertions in two unrelated Indian patients with 5α reductase 2 deficiency leading to premature termination of SRD5A2 enzyme. 2013 Dec 11 2
25 22707254 Association of V89L SRD5A2 polymorphism with craving and serum leptin levels in male alcohol addicts. 2012 Dec 2
26 20349245 Practical approach to steroid 5alpha-reductase type 2 deficiency. 2011 Jan 1
27 21177315 Meta-analysis of three polymorphisms in the steroid-5-alpha-reductase, alpha polypeptide 2 gene (SRD5A2) and risk of prostate cancer. 2011 May 2
28 21290231 Specific pharmacokinetic aspects of the urinary tract. 2011 1
29 21511288 Hypospadias risk and polymorphism in SRD5A2 and CYP17 genes: case-control study among Indian children. 2011 Jun 1
30 20018190 Cloning and differential expression of steroid 5 alpha-reductase type 1 (Srd5a1) and type 2 (Srd5a2) from the Harderian glands of hamsters. 2010 Apr 1 1
31 20056642 Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer. 2010 Jan 1
32 20151762 Changes of metabolic profile in men treated for androgenetic alopecia with 1 mg finasteride. 2010 Jan 1
33 20511729 The IVS1-2A>G mutation in the SRD5A2 gene predominates in Cypriot patients with 5α reductase deficiency. 2010 Dec 2
34 20823678 Establishment of a novel model for studying the effects of extracts of Chinese herb medicine on human type II 5alpha-reductase in vitro. 2010 Sep 1
35 19443907 Longer (TA)n repeat but not A49T and V89L polymorphisms in SRD5A2 gene may confer prostate cancer risk in South Indian men. 2009 Nov-Dec 2
36 19492581 Genetic analysis of the SRD5A2 gene in Indian patients with 5alpha-reductase deficiency. 2009 Mar 1
37 17609295 Molecular characterization of 6 unrelated Italian patients with 5alpha-reductase type 2 deficiency. 2008 Jan-Feb 1
38 18350250 Novel compound heterozygous mutations in the SRD5A2 gene from 46,XY infants with ambiguous external genitalia. 2008 1
39 18469342 No association between the SRD5A2 gene A49T missense variant and prostate cancer risk: lessons learned. 2008 Aug 15 1
40 18483391 VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men. 2008 May 15 1
41 18780294 The SRD5A2 V89L polymorphism is associated with severity of disease in men with early onset prostate cancer. 2008 Dec 1 1
42 19169095 Finasteride-induced myalgia and HyperCKemia. 2008 Dec 1
43 19246976 Polymorphisms of steroid 5-alpha-reductase type I (SRD5A1) gene are associated to peripheral arterial disease. 2008 Dec 1
44 17283174 Impaired dihydrotestosterone catabolism in human prostate cancer: critical role of AKR1C2 as a pre-receptor regulator of androgen receptor signaling. 2007 Feb 1 1
45 17646096 Establishment of type II 5alpha-reductase over-expressing cell line as an inhibitor screening model. 2007 Nov-Dec 2
46 17823934 SRD5A2 and HSD3B2 polymorphisms are associated with prostate cancer risk and aggressiveness. 2007 Nov 1 1
47 15813602 5alpha-reductase 2 gene mutations in three unrelated patients of Greek Cypriot origin: identification of an ancestral founder effect. 2005 Mar 2
48 15844467 Choice of gender in 5alpha-reductase deficiency: a moving target. 2005 Apr 1
49 16155734 Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1. 2005 1
50 16181229 SRD5A2 gene analysis in an Italian population of under-masculinized 46,XY subjects. 2005 Oct 2