1H-(1,2,3)oxadiazolo(4,4-a)quinoxalin-1-one

guanylate cyclase 1 soluble subunit beta 2 ; Rattus norvegicus







57 Article(s)
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1 33613315 Downregulation of Soluble Guanylate Cyclase and Protein Kinase G With Upregulated ROCK2 in the Pulmonary Artery Leads to Thromboxane A2 Sensitization in Monocrotaline-Induced Pulmonary Hypertensive Rats. 2021 1
2 34552483 ET-CORM Mediated Vasorelaxation of Small Mesenteric Arteries: Involvement of Kv7 Potassium Channels. 2021 1
3 32581821 Mechanisms Associated to Nitroxyl (HNO)-Induced Relaxation in the Intestinal Smooth Muscle. 2020 2
4 29773995 Hypoxia/Reoxygenation of Rat Renal Arteries Impairs Vasorelaxation via Modulation of Endothelium-Independent sGC/cGMP/PKG Signaling. 2018 2
5 28115173 Cyclosporine counteracts endotoxemia-evoked reductions in blood pressure and cardiac autonomic dysfunction via central sGC/MAPKs signaling in rats. 2017 Feb 15 1
6 28159537 Diethyl-4,4'-dihydroxy-8,3'-neolign-7,7'-dien-9,9'-dionate exhibits antihypertensive activity in rats through increase in intracellular cGMP level and blockade of calcium channels. 2017 Mar 15 2
7 28192151 Angiotensin-(1-7)-dependent vasorelaxation of the renal artery exhibits unique angiotensin and bradykinin receptor selectivity. 2017 Apr 2
8 28444988 Inhibitory action of oxytocin on spontaneous contraction of rat distal colon by nitrergic mechanism: involvement of cyclic GMP and apamin-sensitive K+ channels. 2017 Nov 3
9 28655348 The Carbon monoxide releasing molecule ALF-186 mediates anti-inflammatory and neuroprotective effects via the soluble guanylate cyclase ß1 in rats' retinal ganglion cells after ischemia and reperfusion injury. 2017 Jun 27 1
10 28679626 The bradykinin-cGMP-PKG pathway augments insulin sensitivity via upregulation of MAPK phosphatase-5 and inhibition of JNK. 2017 Sep 1 1
11 27009048 The vasodilatory effect of sulfur dioxide via SGC/cGMP/PKG pathway in association with sulfhydryl-dependent dimerization. 2016 Jun 1 1
12 27148059 The Role of cGMP on Adenosine A 1 Receptor-mediated Inhibition of Synaptic Transmission at the Hippocampus. 2016 1
13 27158388 The regulation of sGC on the rat model of neuropathic pain is mediated by 5-HT1ARs and NO/cGMP pathway. 2016 2
14 25960756 Vasorelaxant and Hypotensive Effects of Jaboticaba Fruit (Myrciaria cauliflora) Extract in Rats. 2015 2
15 24576493 Effect of diet-induced obesity on BK(Ca) function in contraction and dilation of rat isolated middle cerebral artery. 2014 Apr 1
16 24658016 Vasodilator responses to acetylcholine are not mediated by the activation of soluble guanylate cyclase or TRPV4 channels in the rat. 2014 Jun 1 2
17 24964291 Nitric oxide as a target for the hypotensive and vasorelaxing effects induced by (Z)-ethyl 12-nitrooxy-octadec-9-enoate in rats. 2014 Oct 1 1
18 25458534 Role of CB2 receptors and cGMP pathway on the cannabinoid-dependent antiepileptic effects in an in vivo model of partial epilepsy. 2014 Dec 1
19 23593279 Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway. 2013 1
20 24144050 Investigation of the role of the NO-cGMP pathway on YC-1 and DEA/NO effects on thoracic aorta smooth muscle responses in a rat preeclampsia model. 2013 Oct 1
21 21311889 Nitric oxide effects depend on different mechanisms in different regions of the rat heart. 2012 Jan 2
22 21756248 Acetylsalicylic acid regulates overexpressed small GTPase RhoA in vascular smooth muscle cells through prevention of new synthesis and enhancement of protein degradation. 2012 Apr 1 2
23 22659114 YC-1, a potent antithrombotic agent, induces lipolysis through the PKA pathway in rat visceral fat cells. 2012 Aug 15 2
24 22798015 Vasorelaxing effects of estetrol in rat arteries. 2012 Oct 1
25 21063768 Protective effects of YC-1 against glutamate induced PC12 cell apoptosis. 2011 Mar 1
26 21217076 Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme. 2011 Mar 2
27 21354320 Activation of MEK1/ERK1/2/iNOS/sGC/PKG pathway associated with peroxynitrite formation contributes to hypotension and vascular hyporeactivity in endotoxemic rats. 2011 Apr 30 1
28 22073284 Inhibition of striatal soluble guanylyl cyclase-cGMP signaling reverses basal ganglia dysfunction and akinesia in experimental parkinsonism. 2011 2
29 19969007 Nitric oxide-soluble guanylyl cyclase signaling regulates corticostriatal transmission and short-term synaptic plasticity of striatal projection neurons recorded in vivo. 2010 Mar 1
30 20933607 Anti-aggregating effect of BAY 58-2667, an activator of soluble guanylyl cyclase. 2010 Nov-Dec 1
31 21224496 Phosphodiesterase 3A expression is modulated by nitric oxide in rat pulmonary artery smooth muscle cells. 2010 Dec 1
32 18022154 Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis. 2008 Jan 28 1
33 18046020 Calcium/calmodulin-dependent kinase II mediates NO-elicited PKG activation to participate in spinal reflex potentiation in anesthetized rats. 2008 Feb 1
34 18082639 trans-Arachidonic acids induce a heme oxygenase-dependent vasorelaxation of cerebral microvasculature. 2008 Mar 1 2
35 18408126 High-fat diet-induced obesity leads to increased NO sensitivity of rat coronary arterioles: role of soluble guanylate cyclase activation. 2008 Jun 2
36 18539756 Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall. 2008 Aug 3
37 18806822 Desensitization of the soluble guanylyl cyclase/cGMP pathway by lipopolysaccharide in rat isolated pulmonary artery but not aorta. 2008 Dec 1
38 16941138 Role of the locus coeruleus carbon monoxide pathway in endotoxin fever in rats. 2007 Jan 1
39 17189622 The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature. 2007 Feb 1 1
40 16203165 Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction. 2006 1
41 16391173 Vasorelaxing effect of BAY 41-2272 in rat basilar artery: involvement of cGMP-dependent and independent mechanisms. 2006 Mar 1
42 16517024 Ammonia affects the activity and expression of soluble and particulate GC in cultured rat astrocytes. 2006 May-Jun 1
43 16901472 Central heme oxygenase-carbon monoxide pathway participates in the lipopolysaccharide-induced tolerance in rats. 2006 Sep 21 2
44 15993634 Multiple potassium channels mediate nitric oxide-induced inhibition of rat vascular smooth muscle cell proliferation. 2005 Sep 2
45 14654104 Contribution of cGMP but not peroxynitrite to negative feedback regulation of penile erection elicited by nitric oxide in the hippocampal formation of the rat. 2004 Jan 1
46 14715697 Synthesis of nitric oxide in postganglionic myenteric neurons during endotoxemia: implications for gastric motor function in rats. 2004 Mar 3
47 14975671 GABA(A), but not NMDA, receptors modulate in vivo NO-mediated cGMP synthesis in the rat cerebral cortex. 2004 Mar 1
48 12598412 Differential engagements of glutamate and GABA receptors in cardiovascular actions of endogenous nNOS or iNOS at rostral ventrolateral medulla of rats. 2003 Feb 1
49 12742382 Nitric oxide inhibits spleen cell proliferative response after burn injury by inducing cytostasis, apoptosis, and necrosis of activated T lymphocytes: role of the guanylate cyclase. 2003 Jan 2
50 14586658 Mechanism of the positive contractile effect of nitric oxide on rat ventricular cardiomyocytes with positive force/frequency relationship. 2003 Dec 2