| 1 |
35104454 | Multiple PDE3A modulators act as molecular glues promoting PDE3A-SLFN12 interaction and induce SLFN12 dephosphorylation and cell death. | 2022 Jun 16 |
4 |
| 2 |
35209923 | Signaling mechanisms and their regulation during in vivo or in vitro maturation of mammalian oocytes. | 2022 Feb 24 |
3 |
| 3 |
35351662 | Finding the "switch" in platelet activation: prediction of key mediators involved in reversal of platelet activation using a novel network biology approach. | 2022 Jun 15 |
1 |
| 4 |
33249558 | Identification and functional study of genetic polymorphisms in cyclic nucleotide phosphodiesterase 3A (PDE3A). | 2021 Mar |
6 |
| 5 |
33660401 | Local cyclic adenosine monophosphate signalling cascades-Roles and targets in chronic kidney disease. | 2021 May |
2 |
| 6 |
34230953 | [Research progress of cyclic adenosine monophosphate in mammalian follicular development]. | 2021 Jun 25 |
5 |
| 7 |
34671065 | Dynamic FRET-FLIM based screening of signal transduction pathways. | 2021 Oct 20 |
1 |
| 8 |
31871268 | Phosphodiesterase 3A Represents a Therapeutic Target that Drives Stem Cell-like Property and Metastasis in Breast Cancer. | 2020 Mar |
1 |
| 9 |
32914566 | Nitric oxide activates AMPK by modulating PDE3A in human pulmonary artery smooth muscle cells. | 2020 Sep |
1 |
| 10 |
30871701 | A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium. | 2019 Mar 19 |
8 |
| 11 |
31401933 | High cGMP and low PDE3A activity are associated with oocyte meiotic incompetence. | 2019 Oct |
1 |
| 12 |
27865066 | Newly synthesized cAMP is integrated at a membrane protein complex signalosome to ensure receptor response specificity. | 2017 Jan |
2 |
| 13 |
28506928 | Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells. | 2017 Aug |
4 |
| 14 |
29216268 | Docking and quantitative structure-activity relationship of bi-cyclic heteroaromatic pyridazinone and pyrazolone derivatives as phosphodiesterase 3A (PDE3A) inhibitors. | 2017 |
1 |
| 15 |
26460717 | Regulation of cAMP Intracellular Levels in Human Platelets Stimulated by 2-Arachidonoylglycerol. | 2016 May |
1 |
| 16 |
26934198 | Design and Development of Novel 4-(4-(1H-Tetrazol-5-yl)-1H-pyrazol-1-yl)-6-morpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine as Cardiotonic Agent via Inhibition of PDE3. | 2016 Apr |
4 |
| 17 |
27053290 | A PDE3A mutation in familial hypertension and brachydactyly syndrome. | 2016 Aug |
1 |
| 18 |
27647936 | Effects of heterologous expression of human cyclic nucleotide phosphodiesterase 3A (hPDE3A) on redox regulation in yeast. | 2016 Nov 15 |
2 |
| 19 |
28959341 | Expression of Recombinant Phosphodiesterases 3A and 3B Using Baculovirus Expression System. | 2016 Dec |
5 |
| 20 |
25593322 | Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. | 2015 Mar 13 |
4 |
| 21 |
25961942 | PDE3A mutations cause autosomal dominant hypertension with brachydactyly. | 2015 Jun |
1 |
| 22 |
26018892 | Hypertension linked to PDE3A activation. | 2015 Jun |
1 |
| 23 |
26095046 | Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy. | 2015 Jul 2 |
1 |
| 24 |
26283042 | Clinical effects of phosphodiesterase 3A mutations in inherited hypertension with brachydactyly. | 2015 Oct |
1 |
| 25 |
24341287 | In vitro effects of cilostazol, a phosphodiesterase 3A inhibitor, on mouse oocyte maturation and morphology. | 2014 Feb |
2 |
| 26 |
22692928 | Cyclic nucleotide phosphodiesterase 3 signaling complexes. | 2012 Sep |
2 |
| 27 |
20568115 | Reactive oxygen and nitrogen species during meiotic resumption from diplotene arrest in mammalian oocytes. | 2010 Oct 15 |
2 |
| 28 |
19332778 | Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity. | 2009 Apr 14 |
4 |
| 29 |
18006600 | Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A. | 2008 Jan |
2 |
| 30 |
18394675 | A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A. | 2008 Jun |
1 |
| 31 |
17218408 | 3'5'-cyclic adenosine monophosphate-dependent up-regulation of phosphodiesterase type 3A in porcine cumulus cells. | 2007 Apr |
2 |
| 32 |
17392505 | Thrombin regulates intracellular cyclic AMP concentration in human platelets through phosphorylation/activation of phosphodiesterase 3A. | 2007 Sep 1 |
6 |
| 33 |
17704206 | Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3. | 2007 Oct 12 |
1 |
| 34 |
16873361 | New insights from the structure-function analysis of the catalytic region of human platelet phosphodiesterase 3A: a role for the unique 44-amino acid insert. | 2006 Sep 29 |
2 |
| 35 |
17038172 | New insight into the role of phosphodiesterase 3A in porcine oocyte maturation. | 2006 Oct 12 |
1 |
| 36 |
15627479 | Dexamethasone down-regulates cAMP-phosphodiesterase in human osteosarcoma cells. | 2005 Jan 15 |
1 |
| 37 |
15867171 | Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure. | 2005 May 17 |
1 |
| 38 |
16186489 | A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. | 2005 Oct 11 |
4 |
| 39 |
14645013 | Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels. | 2004 Mar 15 |
2 |
| 40 |
15224131 | Cardiovascular implications in the use of PDE5 inhibitor therapy. | 2004 Jun |
2 |
| 41 |
15254586 | Cyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility. | 2004 Jul |
2 |
| 42 |
15265792 | Protein kinase A mediates inhibition of the thrombin-induced platelet shape change by nitric oxide. | 2004 Nov 1 |
1 |
| 43 |
15354266 | Platelet cyclic adenosine monophosphate phosphodiesterases: targets for regulating platelet-related thrombosis. | 2004 Aug |
1 |
| 44 |
11832336 | PKA-dependent activation of PDE3A and PDE4 and inhibition of adenylyl cyclase V/VI in smooth muscle. | 2002 Mar |
1 |
| 45 |
11863434 | A nonhydrolyzable reactive cAMP analogue, (S(p))-8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic S-(methyl)monophosphorothioate, irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase at micromolar concentrations. | 2002 Mar 5 |
7 |
| 46 |
11955000 | A new nonhydrolyzable reactive cAMP analog, (Sp)-adenosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase. | 2002 Feb |
2 |
| 47 |
12038792 | Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases. | 2002 May |
10 |
| 48 |
11468344 | Identification of overlapping but distinct cAMP and cGMP interaction sites with cyclic nucleotide phosphodiesterase 3A by site-directed mutagenesis and molecular modeling based on crystalline PDE4B. | 2001 Aug |
3 |
| 49 |
10908291 | Dual expression and differential regulation of phosphodiesterase 3A and phosphodiesterase 3B in human vascular smooth muscle: implications for phosphodiesterase 3 inhibition in human cardiovascular tissues. | 2000 Aug |
2 |
| 50 |
9031467 | Isolation and regulation of the cGMP-inhibited cAMP phosphodiesterase in human erythroleukemia cells. | 1997 Jan |
2 |