| 1 |
33550096 | Alternative regulation of HIF-1α stability through Phosphorylation on Ser451. | 2021 Mar 19 |
1 |
| 2 |
31618435 | Prolyl Hydroxylase Inhibition Mitigates Pouchitis. | 2020 Jan 6 |
1 |
| 3 |
31760602 | Purification and Characterization of Prolyl Hydroxylase 3/Pyruvate Kinase Isoform 2 Protein Complex. | 2020 Feb |
4 |
| 4 |
30617181 | Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma. | 2019 Mar 8 |
2 |
| 5 |
29339541 | PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα. | 2018 Apr 1 |
4 |
| 6 |
27881662 | The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function. | 2017 Jan 15 |
2 |
| 7 |
28680592 | HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma. | 2017 |
1 |
| 8 |
29051216 | Prolyl 4-Hydroxylase Domain Protein 3 Overexpression Improved Obstructive Sleep Apnea-Induced Cardiac Perivascular Fibrosis Partially by Suppressing Endothelial-to-Mesenchymal Transition. | 2017 Oct 19 |
2 |
| 9 |
29206844 | Restoration of the prolyl-hydroxylase domain protein-3 oxygen-sensing mechanism is responsible for regulation of HIF2α expression and induction of sensitivity of myeloma cells to hypoxia-mediated apoptosis. | 2017 |
4 |
| 10 |
25550320 | Morg1 heterozygous deficiency ameliorates hypoxia-induced acute renal injury. | 2015 Mar 15 |
2 |
| 11 |
25809665 | Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing. | 2015 Jun |
1 |
| 12 |
26223520 | Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27. | 2015 Jul 30 |
2 |
| 13 |
26296657 | pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation. | 2015 Nov |
1 |
| 14 |
25420773 | Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. | 2014 Nov 25 |
1 |
| 15 |
23345396 | p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation. | 2013 Mar 1 |
1 |
| 16 |
23380539 | The regulation, localization, and functions of oxygen-sensing prolyl hydroxylase PHD3. | 2013 Apr |
2 |
| 17 |
24672806 | Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein. | 2013 Oct 1 |
1 |
| 18 |
22395314 | Molecular oxygen sensing: implications for visceral surgery. | 2012 Apr |
1 |
| 19 |
22898032 | Construction of a recombinant eukaryotic expression vector containing PHD3 gene and its expression in HepG2 cells. | 2012 Aug 17 |
2 |
| 20 |
21483450 | The oxygen sensor PHD3 limits glycolysis under hypoxia via direct binding to pyruvate kinase. | 2011 Jun |
1 |
| 21 |
21785006 | Regulation of metabolism by hypoxia-inducible factor 1. | 2011 |
1 |
| 22 |
21951999 | PHD1 interacts with ATF4 and negatively regulates its transcriptional activity without prolyl hydroxylation. | 2011 Dec 10 |
1 |
| 23 |
19922526 | Normoxic destabilization of ATF-4 depends on proteasomal degradation. | 2010 Apr |
3 |
| 24 |
20028863 | Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors. | 2010 Jan 1 |
1 |
| 25 |
19546213 | Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38. | 2009 Aug 21 |
1 |
| 26 |
19584355 | Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. | 2009 Jul 7 |
1 |
| 27 |
18337469 | Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation. | 2008 May |
4 |
| 28 |
18927305 | Overexpression of the oxygen sensors PHD-1, PHD-2, PHD-3, and FIH Is associated with tumor aggressiveness in pancreatic endocrine tumors. | 2008 Oct 15 |
2 |
| 29 |
18980986 | Identification of an immunogenic CTL epitope of HIFPH3 for immunotherapy of renal cell carcinoma. | 2008 Nov 1 |
2 |
| 30 |
17684156 | Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor. | 2007 Nov 15 |
4 |
| 31 |
17725546 | Identification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains. | 2007 Dec 1 |
1 |
| 32 |
16473674 | An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity. | 2006 Feb 20 |
1 |
| 33 |
16509823 | Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation. | 2006 Jul 1 |
1 |
| 34 |
16565084 | Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. | 2006 Jun 2 |
1 |
| 35 |
16611863 | Dynamic HIF1A regulation during human placental development. | 2006 Jul |
1 |
| 36 |
15563275 | Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element. | 2005 May 1 |
1 |
| 37 |
15251459 | The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin. | 2004 Jul 16 |
1 |
| 38 |
15474027 | Determination and comparison of specific activity of the HIF-prolyl hydroxylases. | 2004 Oct 8 |
1 |
| 39 |
12615973 | Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing. | 2003 Apr 1 |
2 |
| 40 |
14506252 | The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen. | 2003 Dec 5 |
1 |
| 41 |
12234095 | Mammalian EGLN genes have distinct patterns of mRNA expression and regulation. | 2002 |
1 |