Irinotecan

ATP binding cassette subfamily C member 4 ; Homo sapiens







9 Article(s)
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1 30634695 A Human ABC Transporter ABCC4 Gene SNP (rs11568658, 559 G > T, G187W) Reduces ABCC4-Dependent Drug Resistance. 2019 Jan 10 1
2 28677646 Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4. 2017 Jul 4 2
3 28735070 Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo. 2017 Sep 1
4 26950035 MRP1 expression in CTCs confers resistance to irinotecan-based chemotherapy in metastatic colorectal cancer. 2016 Aug 15 2
5 25462817 Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen. 2015 Feb 1 2
6 25762723 Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea. 2015 May 1 2
7 18690847 Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy. 2008 Aug 1
8 15827327 Expression of multidrug transporter MRP4/ABCC4 is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan in vitro. 2005 Apr 2
9 16132345 Human multidrug resistance associated protein 4 confers resistance to camptothecins. 2005 Nov 8