Cyclic AMP

ATP binding cassette subfamily C member 4 ; Homo sapiens







35 Article(s)
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1 32333821 MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux. 2021 Jan 3
2 33441643 Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells. 2021 Jan 13 5
3 33529712 Interactions between ABCC4/MRP4 and ABCC7/CFTR in human airway epithelial cells in lung health and disease. 2021 Apr 1
4 33851387 Role of Membrane Lipid Rafts in MRP4 (ABCC4) Dependent Regulation of the cAMP Pathway in Blood Platelets. 2021 Dec 3
5 34666750 Potentiation of long-acting β2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP. 2021 Oct 19 5
6 32553977 Multidrug resistance protein 4 (MRP4/ABCC4) is overexpressed in clear cell renal cell carcinoma (ccRCC) and is essential to regulate cell proliferation. 2020 Oct 15 1
7 29284392 MRP4/ABCC4 As a New Therapeutic Target: Meta-Analysis to Determine cAMP Binding Sites as a Tool for Drug Design. 2019 3
8 31043460 Identification of MRP4/ABCC4 as a Target for Reducing the Proliferation of Pancreatic Ductal Adenocarcinoma Cells by Modulating the cAMP Efflux. 2019 Jul 14
9 31381460 Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4. 2019 Dec 1
10 31481727 Phosphorylation-dependent modulation of CFTR macromolecular signalling complex activity by cigarette smoke condensate in airway epithelia. 2019 Sep 3 4
11 29448294 Impact of Multidrug Resistance Protein-4 Inhibitors on Modulating Platelet Function and High on-Aspirin Treatment Platelet Reactivity. 2018 Mar 2
12 28204955 Inactivation of Non-canonical Cyclic Nucleotides: Hydrolysis and Transport. 2017 1
13 27063943 MRP4 (ABCC4) as a potential pharmacologic target for cardiovascular disease. 2016 May 3
14 25762723 Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea. 2015 May 1 3
15 25790437 Dual role of cAMP in the transcriptional regulation of multidrug resistance-associated protein 4 (MRP4) in pancreatic adenocarcinoma cell lines. 2015 9
16 25841995 PKA and actin play critical roles as downstream effectors in MRP4-mediated regulation of fibroblast migration. 2015 Jul 3
17 26206993 [Contemporary concepts in studies on cyclic AMP and its role in the inflammatory reaction]. 2015 Jul 14 1
18 24454870 Prognostic significance and molecular mechanism of ATP-binding cassette subfamily C member 4 in resistance to neoadjuvant radiotherapy of locally advanced rectal carcinoma. 2014 1
19 24510239 ABCC4 copy number variation is associated with susceptibility to esophageal squamous cell carcinoma. 2014 Sep 1
20 25121519 cAMP regulates expression of the cyclic nucleotide transporter MRP4 (ABCC4) through the EPAC pathway. 2014 Oct 2
21 25173977 Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. 2014 Sep 1
22 23385799 MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure. 2013 Mar 5 3
23 23014861 Reduction of cAMP and cGMP inhibitory effects in human platelets by MRP4-mediated transport. 2012 Nov 4
24 21205825 Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation. 2011 Mar 4 4
25 18559527 Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4. 2008 Jun 15 1
26 18636120 Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation. 2008 Aug 1
27 17855498 Transport of a fluorescent cAMP analog in teleost proximal tubules. 2007 Dec 1
28 15454390 Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. 2005 Feb 1
29 15747503 Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5). 2005 1
30 14643890 Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione. 2004 Feb 1
31 12637526 Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells. 2003 May 16 2
32 11802779 Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues. 2002 Feb 1 4
33 11856762 The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. 2002 Mar 5
34 12423063 Role of MRP4 and MRP5 in biology and chemotherapy. 2002 1
35 11447229 Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. 2001 Sep 7 2