Serine

cyclin-dependent kinase 5 ; Mus musculus







39 Article(s)
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1 31807777 Phosphorylation of Tet3 by cdk5 is critical for robust activation of BRN2 during neuronal differentiation. 2020 Feb 20 2
2 32640230 Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin. 2020 Jul 7 2
3 32670025 Metformin Ameliorates Synaptic Defects in a Mouse Model of AD by Inhibiting Cdk5 Activity. 2020 2
4 33240752 CDK5 Inhibition Abrogates TNBC Stem-Cell Property and Enhances Anti-PD-1 Therapy. 2020 Nov 1
5 30375127 Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's model mice. 2019 Jan 2
6 29158185 CDK5-mediated phosphorylation of Sirt2 contributes to depressive-like behavior induced by social defeat stress. 2018 Feb 2
7 29345339 The role of Cdk5-mediated Drp1 phosphorylation in Aβ1-42 induced mitochondrial fission and neuronal apoptosis. 2018 Jun 4
8 27296112 Disruption of neuronal nitric oxide synthase dimerization contributes to the development of Alzheimer's disease: Involvement of cyclin-dependent kinase 5-mediated phosphorylation of neuronal nitric oxide synthase at Ser(293). 2016 Oct 4
9 25409143 An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ. 2015 Jan 15 2
10 25785643 Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex. 2015 1
11 25875370 Anti-diabetes drug pioglitazone ameliorates synaptic defects in AD transgenic mice by inhibiting cyclin-dependent kinase5 activity. 2015 2
12 26093036 A novel phosphorylation site of N-methyl-D-aspartate receptor GluN2B at S1284 is regulated by Cdk5 in neuronal ischemia. 2015 Sep 1
13 26198700 Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727. 2015 Oct 2
14 24658276 Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice. 2014 2
15 24849359 Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses. 2014 May 21 2
16 25100724 A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity. 2014 Sep 19 1
17 25150199 Valproic acid increases NO production via the SH-PTP1-CDK5-eNOS-Ser(116) signaling cascade in endothelial cells and mice. 2014 Nov 3
18 22584573 GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain. 2012 Aug 10 1
19 23064382 TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory. 2012 Nov 1
20 23071094 Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages. 2012 Dec 3
21 21482799 Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta. 2011 Apr 26 1
22 22049418 Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1). 2011 Nov 2 1
23 22078880 Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity. 2011 Nov 11 1
24 20573893 Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity. 2010 Jun 23 1
25 18755796 Cyclin-dependent kinase 5 regulates steroidogenic acute regulatory protein and androgen production in mouse Leydig cells. 2009 Jan 2
26 19587281 Phosphorylation of prion protein at serine 43 induces prion protein conformational change. 2009 Jul 8 1
27 18460467 Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation. 2008 Jun 27 2
28 18616637 Dysfunction of astrocytes in senescence-accelerated mice SAMP8 reduces their neuroprotective capacity. 2008 Oct 1
29 16529723 Modulation of Reelin signaling by Cyclin-dependent kinase 5. 2007 Apr 6 4
30 17009320 cdk5 modulates beta- and delta-catenin/Pin1 interactions in neuronal cells. 2007 Feb 15 2
31 15096606 Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity. 2004 Apr 27 1
32 15471880 Cyclin-dependent kinase 5 phosphorylates serine 31 of tyrosine hydroxylase and regulates its stability. 2004 Dec 24 2
33 15489224 Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription. 2004 Dec 24 1
34 12536148 Tau phosphorylation by cyclin-dependent kinase 5/p39 during brain development reduces its affinity for microtubules. 2003 Mar 21 1
35 12824184 Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival. 2003 Sep 12 2
36 12941275 Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. 2003 Aug 22 1
37 14651959 Divergent roles of GSK3 and CDK5 in APP processing. 2003 Dec 26 2
38 11854007 Cdk5 behind the wheel: a role in trafficking and transport? 2002 Jan 1
39 12077184 Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling. 2002 Jun 15 1