regorafenib

ret proto-oncogene ; Homo sapiens







21 Article(s)
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1 35235141 A patent review on efficient strategies for the total synthesis of pazopanib, regorafenib and lenvatinib as novel anti-angiogenesis receptor tyrosine kinase inhibitors for cancer therapy. 2022 Mar 2 2
2 32052681 Regorafenib sensitizes human breast cancer cells to radiation by inhibiting multiple kinases and inducing DNA damage. 2021 1
3 31608707 The role of PIGF blockade in the treatment of colorectal cancer: overcoming the pitfalls. 2020 Jan 1
4 32207565 Initial in vivo testing of a multitarget kinase inhibitor, regorafenib, by the Pediatric Preclinical Testing Consortium. 2020 Jun 1
5 32457362 Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways. 2020 Aug 1
6 32660121 Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD. 2020 Jul 9 2
7 30940655 Regorafenib Promotes Antitumor Immunity via Inhibiting PD-L1 and IDO1 Expression in Melanoma. 2019 Jul 15 1
8 29359239 The orally available multikinase inhibitor regorafenib (BAY 73-4506) in multiple myeloma. 2018 May 1
9 30069758 Regorafenib. 2018 2
10 29262623 Small molecule inhibitor regorafenib inhibits RET signaling in neuroblastoma cells and effectively suppresses tumor growth in vivo. 2017 Nov 28 4
11 26419617 Involvement of Notch-1 in Resistance to Regorafenib in Colon Cancer Cells. 2016 May 1
12 26651387 The safety of regorafenib for the treatment of gastrointestinal stromal tumors. 2016 Jan 1
13 26865419 Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma. 2016 May 1
14 26327919 Management of regorafenib-related toxicities: a review. 2015 Sep 2
15 24559322 Regorafenib in metastatic colorectal cancer. 2014 Mar 1
16 24744988 Will the Requirement by the US FDA to Simultaneously Co-Develop Companion Diagnostics (CDx) Delay the Approval of Receptor Tyrosine Kinase Inhibitors for RTK-Rearranged (ROS1-, RET-, AXL-, PDGFR-α-, NTRK1-) Non-Small Cell Lung Cancer Globally? 2014 1
17 24756792 Regorafenib. 2014 2
18 23610528 Critical appraisal of the use of regorafenib in the management of colorectal cancer. 2013 1
19 22421192 A phase I dose-escalation study of regorafenib (BAY 73-4506), an inhibitor of oncogenic, angiogenic, and stromal kinases, in patients with advanced solid tumors. 2012 May 1 1
20 22577890 Regorafenib for cancer. 2012 Jun 2
21 21170960 Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. 2011 Jul 1 1