Quinidine

potassium voltage-gated channel subfamily H member 2 ; Homo sapiens







25 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34025432 Effects of Antiarrhythmic Drugs on hERG Gating in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1. 2021 1
2 30582453 Patient-Specific and Gene-Corrected Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Short QT Syndrome. 2019 Jan 4 2
3 31946488 Pharmacotherapeutic Effects of Quinidine on Short QT Syndrome by Using Purkinje-Ventricle Model: A Simulation Study. 2019 Jul 2
4 30687112 In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome. 2018 1
5 28632743 In silico assessment of the effects of quinidine, disopyramide and E-4031 on short QT syndrome variant 1 in the human ventricles. 2017 7
6 25790957 The interaction between delayed rectifier channel alpha-subunits does not involve hetero-tetramer formation. 2015 Sep 1
7 21130771 A novel mutation in the KCNH2 gene associated with short QT syndrome. 2011 Mar 1
8 19528813 The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel. 2009 Jul 1
9 19617705 Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation. 2009 Jul-Aug 4
10 18057887 Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide. 2008 1
11 16960444 The effect of high extracellular potassium on IKr inhibition by anti-arrhythmic agents. 2007 2
12 17711440 In vivo effects of mutant HERG K+ channel inhibition by disopyramide in patients with a short QT-1 syndrome: a pilot study. 2007 Nov 1
13 16842817 Disopyramide is an effective inhibitor of mutant HERG K+ channels involved in variant 1 short QT syndrome. 2006 Sep 2
14 16942825 Short QT syndrome: a case report and review of literature. 2006 Oct 2
15 15673388 Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG. 2005 Jan 4
16 15821840 The influence of extracellular acidosis on the effect of IKr blockers. 2005 Mar 2
17 16041196 A mechanism for the potential proarrhythmic effect of acidosis, bradycardia, and hypokalemia on the blockade of human ether-a-go-go-related gene (HERG) channels. 2005 Jul-Aug 4
18 16226079 Short QT syndrome. Genotype-phenotype correlations. 2005 Oct 2
19 15125690 Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels. 2004 May 2
20 15189761 Comparison of kinetic properties of quinidine and dofetilide block of HERG channels. 2004 Jun 16 2
21 12695533 Voltage-dependent profile of human ether-a-go-go-related gene channel block is influenced by a single residue in the S6 transmembrane domain. 2003 May 4
22 14525949 The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines. 2003 Dec 1
23 12086981 Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine. 2002 Jul 2
24 11602243 An amino acid residue whose change by mutation affects drug binding to the HERG channel. 2001 Oct 12 1
25 10028924 Modulation of HERG potassium channels by extracellular magnesium and quinidine. 1999 Feb 4