| 1 |
33759016 | Binding thermodynamics and interaction patterns of human purine nucleoside phosphorylase-inhibitor complexes from extensive free energy calculations. | 2021 May |
2 |
| 2 |
24767876 | Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots. | 2014 Jul |
2 |
| 3 |
19425594 | Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase. | 2009 Jun 16 |
2 |
| 4 |
17910661 | Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency. | 2007 Nov |
1 |
| 5 |
18086344 | Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies. | 2007 Dec |
1 |
| 6 |
17016779 | Drug evaluation: forodesine - PNP inhibitor for the treatment of leukemia, lymphoma and solid tumor. | 2006 Oct |
2 |
| 7 |
17107284 | Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma. | 2006 Dec |
3 |
| 8 |
12914785 | Crystal structure of human purine nucleoside phosphorylase at 2.3A resolution. | 2003 Aug 29 |
1 |
| 9 |
11707439 | Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum. | 2002 Feb 1 |
1 |
| 10 |
11287638 | Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes. | 2001 Apr 10 |
1 |
| 11 |
2104895 | Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency. | 1990 Jan 15 |
2 |
| 12 |
3137573 | Design of vectors for efficient expression of human purine nucleoside phosphorylase in skin fibroblasts from enzyme-deficient humans. | 1988 Sep |
1 |
| 13 |
2439024 | Central nervous system dysfunction and erythrocyte guanosine triphosphate depletion in purine nucleoside phosphorylase deficiency. | 1987 Apr |
1 |
| 14 |
3120506 | 8-Amino-9-substituted guanines: potent purine nucleoside phosphorylase (PNP) inhibitors. | 1987 Aug |
1 |
| 15 |
3091593 | Expression of human malaria parasite purine nucleoside phosphorylase in host enzyme-deficient erythrocyte culture. Enzyme characterization and identification of novel inhibitors. | 1986 Sep 5 |
1 |
| 16 |
3874778 | On the mechanism of deoxyribonucleoside toxicity in human T-lymphoblastoid cells. Reversal of growth inhibition by addition of cytidine. | 1985 Aug 1 |
1 |
| 17 |
6332120 | Specific cytotoxicity of arabinosylguanine toward cultured T lymphoblasts. | 1984 Sep |
1 |
| 18 |
6428752 | The mechanism of inhibition and "reversal" of mitogen-induced lymphocyte activation in a model of purine-nucleoside phosphorylase deficiency. | 1984 Jul |
2 |
| 19 |
6801134 | Regulation of macrophage-mediated suppression by purine nucleoside phosphorylase substrates. | 1982 May |
2 |
| 20 |
6783354 | Phosphorylation of deoxyguanosine by B and T lymphocytes: evidence against selective trapping of deoxyguanosine by T lymphocytes in purine nucleoside phosphorylase deficiency. | 1980 Dec |
1 |
| 21 |
115660 | Deoxyribonucleoside toxicity in adenosine deaminase and purine nucleoside phosphorylase deficiency: implications for the development of new immunosuppressive agents. | 1978 |
2 |