4-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)piperazin-2-one

dipeptidyl peptidase 4 ; Homo sapiens







24 Article(s)
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1 32926865 Optimization and validation of a fluorogenic dipeptidyl peptidase 4 enzymatic assay in human plasma. 2021 Jan 1 4
2 33245796 Pharmacokinetics and safety of evogliptin in hepatically impaired patients. 2021 Jul 1
3 33401457 Evogliptin Suppresses Calcific Aortic Valve Disease by Attenuating Inflammation, Fibrosis, and Calcification. 2021 Jan 1 1
4 33502058 Cardiovascular safety of evogliptin in patients with type 2 diabetes: A nationwide cohort study. 2021 Jun 1
5 33527807 Clinical Evidence of Evogliptin plus Metformin in Management of Type 2 Diabetes mellitus. 2021 Feb 2
6 34304912 Efficacy and Tolerability of Evogliptin in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis with Bayesian Inference Through a Quality-management System. 2021 Aug 2
7 33051573 Evogliptin, a dipeptidyl peptidase-4 inhibitor, attenuates pathological retinal angiogenesis by suppressing vascular endothelial growth factor-induced Arf6 activation. 2020 Oct 1
8 33122892 Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects. 2020 2
9 33489850 Efficacy and Safety of Novel Dipeptidyl-Peptidase-4 Inhibitor Evogliptin in the Management of Type 2 Diabetes Mellitus: A Meta-Analysis. 2020 Sep-Oct 1
10 31890041 Efficacy and safety of evogliptin in the treatment of type 2 diabetes mellitus in a Brazilian population: a randomized bridging study. 2019 1
11 27761990 Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel dipeptidyl peptidase-4 inhibitor, evogliptin (DA-1229). 2017 Feb 4
12 28058750 Efficacy and safety of adding evogliptin versus sitagliptin for metformin-treated patients with type 2 diabetes: A 24-week randomized, controlled trial with open label extension. 2017 May 1
13 28448688 Efficacy and safety of evogliptin monotherapy in patients with type 2 diabetes and moderately elevated glycated haemoglobin levels after diet and exercise. 2017 Dec 1
14 28503751 In vitro evaluation of potential transporter-mediated drug interactions of evogliptin. 2017 Sep 1
15 28806472 Effects of clarithromycin on the pharmacokinetics of evogliptin in healthy volunteers. 2017 Dec 2
16 29061303 Unique binding mode of Evogliptin with human dipeptidyl peptidase IV. 2017 Dec 16 5
17 27156529 Evogliptin: a new dipeptidyl peptidase inhibitor for the treatment of type 2 diabetes. 2016 Jun 1
18 27570447 Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects. 2016 3
19 25362864 A randomized, double-blind, placebo-controlled, phase II clinical trial to investigate the efficacy and safety of oral DA-1229 in patients with type 2 diabetes mellitus who have inadequate glycaemic control with diet and exercise. 2015 Mar 2
20 26541763 Evogliptin: First Global Approval. 2015 Nov 3
21 25336915 Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers. 2014 8
22 22056373 DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes. 2012 Jan 2 2
23 22943970 Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human study. 2012 Sep 3
24 21570283 Discovery of DA-1229: a potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. 2011 Jun 15 1