gemcitabine

WEE1 G2 checkpoint kinase ; Homo sapiens







13 Article(s)
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1 33485453 Adavosertib plus gemcitabine for platinum-resistant or platinum-refractory recurrent ovarian cancer: a double-blind, randomised, placebo-controlled, phase 2 trial. 2021 Jan 23 2
2 33974709 Gene-Gene Interactions of Gemcitabine Metabolizing-Enzyme Genes hCNT3 and WEE1 for Preventing Severe Gemcitabine-Induced Hematological Toxicity. 2021 Oct 4
3 34753061 Long noncoding RNA NORAD acts as a ceRNA mediates gemcitabine resistance in bladder cancer by sponging miR-155-5p to regulate WEE1 expression. 2021 Dec 1
4 32180106 Targeting MYC-driven replication stress in medulloblastoma with AZD1775 and gemcitabine. 2020 May 1
5 31387179 Enhancement of chemosensitivity by WEE1 inhibition in EGFR-TKIs resistant non-small cell lung cancer. 2019 Sep 2
6 29735549 Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine. 2018 Jun 1 2
7 29895190 The contribution of DNA replication stress marked by high-intensity, pan-nuclear γH2AX staining to chemosensitization by CHK1 and WEE1 inhibitors. 2018 1
8 25774168 Targeting lung cancer through inhibition of checkpoint kinases. 2015 1
9 25965828 Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. 2015 May 30 4
10 26057002 WEE1 kinase polymorphism as a predictive biomarker for efficacy of platinum-gemcitabine doublet chemotherapy in advanced non-small cell lung cancer patients. 2015 Jun 9 2
11 26585231 Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair. 2015 Oct 2
12 23520471 Wee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomas. 2013 1
13 19500427 Discovery of gene expression-based pharmacodynamic biomarker for a p53 context-specific anti-tumor drug Wee1 inhibitor. 2009 Jun 8 1